[VadeRetro]

Thermodyanmically it would appear as if the prion was the most stable form of the protein.

Thermodynamically, we shouldn't be here. There is more going on than little elastic balls clacking around.

[AndrewC]

Thermodynamically, we shouldn't be here.

Switching sides does not help your argument if you intend to keep the same argument. Are you now asserting that evolution violates the 2nd law?