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It depends on what you mean by "real actual flesh" and "real actual blood." Anatomical flesh, no. (No organs, no meat proteins.) Physiological blood, no. (None of the biochemical characteristics or physiological functions of blood. Don't try putting it in your I.V.)

Real (or True) Flesh, yes; and Real (or True) Blood, yes. We have it on His word:

John 6:51-56 I am the living bread that came down from heaven; whoever eats this bread will live forever; and the bread that I will give is my flesh for the life of the world.
The Jews quarreled among themselves, saying, “How can this man give us [his] flesh to eat?”
Jesus said to them, “Amen, amen, I say to you, unless you eat the flesh of the Son of Man and drink his blood, you do not have life within you.
Whoever eats my flesh and drinks my blood has eternal life.
For my flesh is true food, and my blood is true drink. Whoever eats my flesh and drinks my blood remains in me and I in him.

Plwase pay close attention to v.63 where Jesus says "The flesh is of no avail," because He is obviously not referring to "His" flesh. He has just told us that "His" flesh is true food, and "His" flesh avails for eternal life.

No, rather He speaks of "the" flesh. Our fleshly-minded, or shall I say meat-headed, way of thinking about things, which is the sense in which he is using the term "flesh." He is speaking of un-regenerate thinking.

For instance, mixing this up with pagan cannibalism. That would be a fleshly, undiscerning error. Or saying it's not "real" or "true" flesh and blood because all of the appearances (including chemical characteristics) remain of bread and wine. That's another fleshly, undiscerning error.

You don't have to parse this all out. It's beyond human comprehension anyway.

It's sufficient that when you hear Jesus' blessed words, "This is My Body," you say "Amen."

Just "Amen".

Take every thought captive in obedience to Christ.