Not necessarily, of course. Since it was so along ago, it cannot be confirmed 100% that Jesus’s brothers and sisters mentioned in the Bible, were actually His brothers and sisters. But I tend to treat the Bible much as I do the US Constitution. I don’t read into it. I read it as it is written and treat it as it is written. Since Mary and Joseph were a happily married couple, it is not unreasonable that other children followed Jesus’s birth.
Put a lot of thought into this have you? Why is it so important to you? What are their names? How many were there? What ages were they? What other serious bible scholars have studied your line of rational? Are there other historical references to support your speculation?
Unless they all died before the crucifixion, then either (a) they weren’t Mary’s children; or (b) Jesus sinned by giving Mary into John’s care. (It’s a sin to absolve someone else of their obligations under Torah.)
I wasn’t there, you could be right!