Jesus himself said only the father knew when he would return.
I’m going from memory and what I heard from Les Feldick but Revelations says that before the Tribulation happens, Israel has to rebuild its Temple and sign a seven year peace treaty although the treaty might be with the antichrist so the Tribulation has already begun.
I don’t know how Israel is going to convince the Muslims to give up the Dome of the Rock but if they do, the clock starts ticking.
Another prophecy (Isaiah 17) concerns the future destruction of Damascus. It will be completely destroyed and rendered uninhabitable.