You see, rzman21? THIS is why Aquinas is important. The doctrine teaches, almost precisely, that a"simple medical test" would find that the host had all the "accidents" of a baked wafer of wheat flour and water.
In the post Cartesian age "real" does mean what it meant before.
A guy assaulted me once because he thought I was not a REAL Law Enforcement Officer. His error had nothing to do with what could be measured about me. The "reality" (or not) of the presence of Jesus in the Blessed Sacrament cannot be ascertained by tests, well, by none given in this life.
The miracle of the real presence is beyond all human understanding, and the talk of substance and accidents is irrelevant.
It just is. No amount of rationalism can explain matters of faith.
This sort of question of how many angels could dance on the head of a pin is why we where have been since the 17th century.
Eastern Christianity has always believed in the real presence, and I might add no one in the East ever denied it.