http://www.jewishvirtuallibrary.org/jsource/History/Inquisition.html
...In the beginning, the Inquisition dealt only with Christian heretics and did not interfere with the affairs of Jews. However, disputes about Maimonides’ books (which addressed the synthesis of Judaism and other cultures) provided a pretext for harassing Jews and, in 1242, the Inquisition condemned the Talmud and burned thousands of volumes. In 1288, the first mass burning of Jews on the stake took place in France...
...An estimated 31,912 heretics were burned at the stake, 17,659 were burned in effigy and 291,450 made reconciliations in the Spanish Inquisition. In Portugal, about 40,000 cases were tried, although only 1,800 were burned, the rest made penance...