People do it every day, you likely included, all over the world.
Sure. Unbelievers say no constantly to the gospel call or anything that would please God. They will NEVER say yes unless God intervenes. This is what David states when he say,
The Lord shepherds us. He WILL use that rod and staff to guide us to green pastures. He leads us where we should go and restores us for His righteousness sake-not ours. Does this sound the least bit familiar? It's Psalms 23.
Believers are a stiff-neck people who are bent on following their own sin nature. And left to our own devices we would degenerate into the wickedness of the world. Ever served on a staff to pick out carpeting for the church? God guides us past that to work His will. There is no greater evidence in scripture of this than Jonah.