Good question - how might it do that? Would there be a series of indicators that, if lined up, would show that there is no originator of everything? Is that what you mean?
Quite the opposite. Why is there always attempts to prove that God or an “originator of everything” exists? There is arguably a fallacy or better, a flawed assumption being made in all these so-called attempts that God’s existence needs to be proven. In other words, the attempt to prove the existence of God or an “originator of everything” arguably stems from the belief, premise, or basis that for some reason, 1) God’s existence needs to be proven and/or 2) God does not exist. Why not work from the premise that God or an “originator of everything” does exist; therefore use science or math to disprove such an existence. See where I am coming from here?