Think it through in light of a person who would rather have what he can steal from you than subscribe to your notion of morality. You have no way to rationally persuade him he shouldn't . . . rational moral restraint without God is a gamble: it is probability of being caught * harshness of punishment if caught > benefit of committing the crime. Throw in your view of a sense of guilt being biologically determined and you get: probability of being caught * harshness of punishment if caught + discomfort of guilty feelings from committing the crime > benefit of committing the crime. It is not a rational basis for morality . . . it is a calculation of cost benefit with no moral component at all.
My ability or inability to talk someone out of robbing me is irrelevant to whether my concept of morality is rational. A person who steals is making the baseless claim by his actions that he is inherently more valuable than others. If I present you with two E. coli, can you say which is better and more deserving of life? Which house mouse has more inherent value? In the same way, there is no rational basis for claiming one person is "better" than another--it's a meaningless claim. So the thief would be acting irrationally.