The earliest known is to St. James the Great in AD 39, then to Pope Liberius (352), then to Richeldis de Faverche (1061), then to St. Dominic, instituting the Rosary prayer in 1214, then to Saint Simon Stock, instituting the Brown Scapular, in 1251.
Of especial importance to the Americans is the apparition to Juan Diego, 1531, in Villa Guadalupe.
I'm not looking to set you up for some gotcha moment. I figure your a pretty good apologist for the RCC and might know.
My perspective is that the Scriptures only give us one example where humans were sent back to Earth and in that instance it was to meet with Jesus. Thus I am very skeptical about where these apparitions are coming from.