Matthew 12
23And all the people were amazed, and said, Is not this the son of David?
24But when the Pharisees heard it, they said, This fellow doth not cast out devils, but by Beelzebub the prince of the devils.
25And Jesus knew their thoughts, and said unto them, Every kingdom divided against itself is brought to desolation; and every city or house divided against itself shall not stand:
26And if Satan cast out Satan, he is divided against himself; how shall then his kingdom stand?
27And if I by Beelzebub cast out devils, by whom do your children cast them out? therefore they shall be your judges.
28But if I cast out devils by the Spirit of God, then the kingdom of God is come unto you.
29Or else how can one enter into a strong man's house, and spoil his goods, except he first bind the strong man? and then he will spoil his house.
30He that is not with me is against me; and he that gathereth not with me scattereth abroad.
31Wherefore I say unto you, All manner of sin and blasphemy shall be forgiven unto men: but the blasphemy against the Holy Ghost shall not be forgiven unto men.
Wouldn't the greatest disrespect be to come before God without the Holy Spirit in you?
IOW, if you are not saved by Grace through Faith you will not have the Holy Spirit indwelling you and when you are judged you will not be found righteous.
I think this verse is directing us right back to our Saviour Jesus Christ.