That would be pure speculation on my part, as the scripture does not interpret Apocalyptic numerology at all, but yes, I think they represent either the twelve tribes of Israel or the twelve apostles. Twelve generally represents completeness.
Genesis 22:17 That in blessing I will bless thee, and in multiplying I will multiply thy seed as the stars of the heaven, and as the sand which is upon the sea shore; and thy seed shall possess the gate of his enemies;
Genesis 26:4 And I will make thy seed to multiply as the stars of heaven, and will give unto thy seed all these countries; and in thy seed shall all the nations of the earth be blessed;