It is still possible to make a decent living in this country. If you are good at what you do (almost regardless of what it is you do), then you will make a VERY good living.
Despite the soft job market, it's still damned near impossible to find a good young civil engineer these days.
Most of the Next Gen powerplays that will obsolete companies like Accelrys are being developed in R&D facilities in the US. Companies like Accelrys are pretty weak sauce technologically, and won't remain competitive long. Yes, a lot of software development is shipped overseas, but most of that is low-rent software development. Most of the really fancy stuff is done solely in the US.
As a general note on outsourcing software, I think it is relatively clear that it is mostly a fad. Most of the companies that I know have done it (and I've done it myself as well) have been totally underwhelmed by the value proposition in practice. There are a lot of companies in Silicon Valley who would no longer seriously consider outsourcing software development because they tried it and it didn't work. It is difficult to justify the investment when all is said and done -- most of the big outsourcing ventures by major companies is a political move in some of their major growing markets i.e. greasing the politicians of the local governments.