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Artificial Life Experiments Show How Complex Functions Can Evolve
NSF ^ | May 8, 2003 | Staff

Posted on 05/08/2003 10:11:06 AM PDT by Nebullis

Artificial Life Experiments Show How Complex Functions Can Evolve

Arlington, Va.—If the evolution of complex organisms were a road trip, then the simple country drives are what get you there. And sometimes even potholes along the way are important.

An interdisciplinary team of scientists at Michigan State University and the California Institute of Technology, with the help of powerful computers, has used a kind of artificial life, or ALife, to create a road map detailing the evolution of complex organisms, an old problem in biology.

In an article in the May 8 issue of the international journal Nature, Richard Lenski, Charles Ofria, Robert Pennock, and Christoph Adami report that the path to complex organisms is paved with a long series of simple functions, each unremarkable if viewed in isolation. "This project addresses a fundamental criticism of the theory of evolution, how complex functions arise from mutation and natural selection," said Sam Scheiner, program director in the division of environmental biology at the National Science Foundation (NSF), which funded the research through its Biocomplexity in the Environment initiative. "These simulations will help direct research on living systems and will provide understanding of the origins of biocomplexity."

Some mutations that cause damage in the short term ultimately become a positive force in the genetic pedigree of a complex organism. "The little things, they definitely count," said Lenski of Michigan State, the paper's lead author. "Our work allowed us to see how the most complex functions are built up from simpler and simpler functions. We also saw that some mutations looked like bad events when they happened, but turned out to be really important for the evolution of the population over a long period of time."

In the key phrase, "a long period of time," lies the magic of ALife. Lenski teamed up with Adami, a scientist at Caltech's Jet Propulsion Laboratory and Ofria, a Michigan State computer scientist, to further explore ALife.

Pennock, a Michigan State philosopher, joined the team to study an artificial world inside a computer, a world in which computer programs take the place of living organisms. These computer programs go forth and multiply, they mutate and they adapt by natural selection.

The program, called Avida, is an artificial petri dish in which organisms not only reproduce, but also perform mathematical calculations to obtain rewards. Their reward is more computer time that they can use for making copies of themselves. Avida randomly adds mutations to the copies, thus spurring natural selection and evolution. The research team watched how these "bugs" adapted and evolved in different environments inside their artificial world.

Avida is the biologist's race car - a really souped up one. To watch the evolution of most living organisms would require thousands of years – without blinking. The digital bugs evolve at lightening speed, and they leave tracks for scientists to study.

"The cool thing is that we can trace the line of descent," Lenski said. "Out of a big population of organisms you can work back to see the pivotal mutations that really mattered during the evolutionary history of the population. The human mind can't sort through so much data, but we developed a tool to find these pivotal events."

There are no missing links with this technology.

Evolutionary theory sometimes struggles to explain the most complex features of organisms. Lenski uses the human eye as an example. It's obviously used for seeing, and it has all sorts of parts - like a lens that can be focused at different distances - that make it well suited for that use. But how did something so complicated as the eye come to be?

Since Charles Darwin, biologists have concluded that such features must have arisen through lots of intermediates and, moreover, that these intermediate structures may once have served different functions from what we see today. The crystalline proteins that make up the lens of the eye, for example, are related to those that serve enzymatic functions unrelated to vision. So, the theory goes, evolution borrowed an existing protein and used it for a new function.

"Over time," Lenski said, "an old structure could be tweaked here and there to improve it for its new function, and that's a lot easier than inventing something entirely new."

That's where ALife sheds light.

"Darwinian evolution is a process that doesn't specify exactly how the evolving information is coded," says Adami, who leads the Digital Life Laboratory at Caltech. "It affects DNA and computer code in much the same way, which allows us to study evolution in this electronic medium."

Many computer scientists and engineers are now using processes based on principles of genetics and evolution to solve complex problems, design working robots, and more. Ofria says that "we can then apply these concepts when trying to decide how best to solve computational problems."

"Evolutionary design," says Pennock, "can often solve problems better than we can using our own intelligence."


TOPICS: Culture/Society; Miscellaneous; News/Current Events
KEYWORDS: ai; crevolist
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To: AndrewC
That was a reference to your #1423 about him jumping to conclusions that they were different circuits. Look at the diagrams in the link. What do you think?
1,481 posted on 05/15/2003 1:33:49 PM PDT by Nataku X (Never give Bush any power you wouldn't want to give to Hillary.)
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To: Nakatu X
"Because a good magician can do ... something --- shouldn't make you right away jump to the conclusion that it's a real phenomenon." --Richard Feynman
1,482 posted on 05/15/2003 1:42:08 PM PDT by f.Christian (( the VERY sick mind - won't recognize facts -- REALITY -- probability anymore ! ))
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To: f.Christian
f.Christian, genetic programming would have been invented even if evolution was rejected. It's an useful technique, and it does work in certain situations.

The two limiting factors are (1) hardware.. going through many levels of recursion with potentially large populations... and (2) it's hard to define a fitness function (e.g., a measure of how "good" the result is that the computer can "understand".

For example, we can't use genetic algorithms on recipes because there's no computational way to measure how good something will taste. But, for a robot throwing a ball, circuit design, and finding the world's only working program written in Malbolge... GP is great.

In a way, it's a very advanced trail-and-error technique. There's no religious implications about it. I don't even know what AndrewC is trying to accomplish in arguing here--I'm just defending GP as a legitmate, useful technique.
1,483 posted on 05/15/2003 1:49:51 PM PDT by Nataku X (Never give Bush any power you wouldn't want to give to Hillary.)
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To: Nakatu X
Look at the diagrams in the link. What do you think?

Yes, I've seen both. That is why I know they are different. The picture has 17 transistors, the schematic has 18. The pix has the input signal going to 3 transistors connected as diodes, another transistor, and a resistor to ground. The schematic has the input going first through a resistor(RSRC) then to a resistor(R14) to ground, to 6 transistors(Q10,Q5,Q6,Q11,Q15,Q7 -- Q15 is diode configured) and to another resistor(R10) to ground

1,484 posted on 05/15/2003 1:52:12 PM PDT by AndrewC
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To: Nakatu X
That was a reference to your #1423 about him jumping to conclusions that they were different circuits.

Well, the jumping to conclusion, was not that the circuits were different, rather that they produced a better circuit and presented that. "I do not know why but they are different" is not jumping to a conclusion.

1,485 posted on 05/15/2003 1:56:51 PM PDT by AndrewC
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To: Nebullis
"Here's this computer program WE made up that seems to suggest that we are right....hmmm....yeah, right.
1,486 posted on 05/15/2003 1:58:55 PM PDT by BSunday
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To: Nakatu X
If I learn french that is evolution ... if I quit drinking --- that is evolution too !


1,487 posted on 05/15/2003 2:01:36 PM PDT by f.Christian (( the VERY sick mind - won't recognize facts -- REALITY -- probability anymore ! ))
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To: f.Christian
Why don't you try quitting drinking, your posts might make more sense.
1,488 posted on 05/15/2003 4:44:24 PM PDT by Lurking Libertarian (Non sub homine, sed sub Deo et lege)
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To: Ichneumon
You're really off to a bad start. "40 new animal phyla"?

You want to play the numbers game? Well at least I have facts to suppor it:

Described recently as "the most important evolutionary event during the entire history of the Metazoa," the Cambrian explosion established virtually all the major animal body forms -- Bauplane or phyla -- that would exist thereafter, including many that were 'weeded out' and became extinct. Compared with the 30 or so extant phyla, some people estimate that the Cambrian explosion may have generated as many as 100. The evolutionary innovation of the Precambrian/Cambrian boundary had clearly been extremely broad: "unprecedented and unsurpassed," as James Valentine of the University of California, Santa Barbara, recently put it (Lewin, 1988).

The important point is that there were a lot. Even more important, there have not been any new animal phyla since the Cambrian (the last missing phyla known at present, vertebrates, were recently found. A fish, with eyes and very much looking like any fish around nowadays).

As for "arose during the Cambrian", you might want to show your research on *that*

Now you are really going off the deep end. Aside from sponges and perhaps worms there were no other multi-cellular animals before the Cambrian. In a mere period of less than 10 million years a multitude of completely new life forms appeared:

Taxa recognized as orders during the (Precambrian-Cambrian) transition chiefly appear without connection to an ancestral clade via a fossil intermediate. This situation is in fact true of most invertebrate orders during the remaining Phanerozoic as well. There are no chains of taxa leading gradually from an ancestral condition to the new ordinal body type. Orders thus appear as rather distinctive subdivisions of classes rather than as being segments in some sort of morphological continuum.
* Valentine, J.W., Awramik, S.M., Signor, P.W., and Sadler, P.M. (1991)
"The Biological Explosion at the Precambrian-Cambrian Boundary"
Evolutionary Biology, Vol. 25, Max K. Hecht, editor, Plenum Press, New York and London, p.284

Furthermore, you'll note that phyla Cnidaria most certainly arose *before* the Cambrian. So if you're aware of any evidence that *all* phyla demonstrably arose *during* the Cambrian, feel free to present it now.

I did not say that. I did say that no new animal phyla have arisen after the Cambrian and that there is no way that evolutionary ancestors can even be postulated for the vast majority of them. Since you admit that only ONE (1) multicellular phyla existed before the Cambrian, my statements are correct by your own admission.

Also let me note here that we are trying to discuss here scientific facts. This is not a personal issue, it is about the truth and the truth is that the Cambrian is totally unexplainable according to evolutionary theory and totally disproves it.

Wow, not only are you the only person on the planet who knows for sure *when* all the animal phyla arose, you know exactly *how quickly* they did so! You must be psychic! Or at least delusional.

As usual, instead of presenting facts showing me to be wrong, you instead insult. There are two reasons for this:
1. you hope to bluff your way out of a fact that contradicts your theory with bluster.
2. you are too lazy and too lame to look at the facts for yourself.

I am not too lazy or too lame to look up the facts, here is support for my statement from the University of Bristol site:

3 billion years went by before complex multicellular life appeared, but when it did it only took between 5 and 10 million years for all the basic body plans of the organisms we see around us today to be established. This is why the origin of multicellular life, in particular the metazoans or large animals with complex body plans, is termed the Cambrian explosion.
From: The Cambrian Explosion"

DNA analysis of modern phyla

You cannot measure a distance when all you know is the end point. DNA analysis of modern phyla cannot give us any such information because we do not know what the DNA of these organisms was some 500 million years ago. This is trying to prove evolution by assuming evolution which is total circular reasoning and total bunk.

As to the rest of your talk about the difficulty of dating strata and so forth, well, it seems to me that evolutionisits always tell us that dating techniques are very specific and can tell us almost what day of the week a new species arose (/sarcasm). The research and dating were done by mostly evolutionist paleontologists (are there any others?) so you cannot give us this dating nonsense as an excuse. Further, the vast majority of these new phyla, which by themselves represent the greatest example of the Cambrian, the Burgess Shale find, is in one place and all the fossils are close in time. It cannot be denied with your obfuscating tactics.

As I have said before, the evidence is so strong for the sudden arising of all these phyla, that the famous atheist/materialist/charlatan of evolution S.J. Gould gave up on Darwinian gradualism because of it.

For a thorough and up to date discussion on the Cambrian those interested might check out The Cambrian Explosion - Biology's Big Bang .

1,489 posted on 05/15/2003 8:09:56 PM PDT by gore3000
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To: donh
I have often pointed out that materialism is anti-science, thanks for proving my point. -me-

Kindly submit your proof of the actual tangible existence of a law of gravity, which does not employ the formulation of humans of said law. The law of gravity and God stand on equal footing, in terms of being, at bottom, manifestations of faith.

Thanks for proving my point again. Since gravity (to you) is a matter of belief, then perhaps you will be willing to jump off a 20 story building to prove that it is wrong? I doubt you are as foolish with your life as you are in your efforts to contradict anything an opponent says.

1,490 posted on 05/15/2003 8:13:31 PM PDT by gore3000
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To: donh
Without natural selection there is no 'how' to evolution, with natural selection evolution is impossible. -me-

So you claim, once again, without the slightest hint of sensible evidence for your absurd contention that it all started with prokariotes.

No donh, it all started with God. It is you who is throwing around prokaryotes (bacteria). I could care less about them. You are in no way responding to my argument against evolution that fitness, due to what we know about organisms today, is a totally impossible agent for transforming a species into another. You yourself gave the reason why:

It's a truism of entomology (been demonstrated in sealed mason jars thousands of times) that when two nearly identical species occupy nearly the same contained biological nitche, one or the other will eventually prevail entirely, no matter how tiny its differential advantage.
1,012 posted on 05/09/2003 9:59 PM PDT by donh ).

Since even the slightest disadvantage will destroy a change, and it takes numerous changes to destroy a species, it is impossible for all of them to be beneficial, hence transformation of one species into another is impossible. Since is the only agent ever proposed for evolution sifting random changes and becoming a deux ex machina in its effort to replace God as the Creator of all things, evolution is thus rendered to be impossible.

1,491 posted on 05/15/2003 8:23:59 PM PDT by gore3000
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To: Ichneumon
Trollish Behavior #9:

Seems that is the new all purpose insult used by evolutionists at anyone who dares to debate them. Now it seems to me that it is the evolutionists, who insult in every post, refuse to answer questions, refuse to address the facts presented to them, refuse to back up their assertions, and gang up on opponents that are the true trolls of these threads.

1,492 posted on 05/15/2003 8:28:51 PM PDT by gore3000
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To: donh
it is unpursuasive to offer as evidence that because humans designed a particular circuit, it is therefore the only candidate to have been designed.

Then how about giving us an example of a circuit that was not humanly designed? How about giving us an example of a circuit that assembled itself? How about showing us how a pile of garbage organized itself into a tv set, a car, an airplane?

Your materialist dreams are not evidence, facts, real life examples are what counts.

1,493 posted on 05/15/2003 8:32:21 PM PDT by gore3000
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To: gore3000
Then how about giving us an example of a circuit that was not humanly designed?

Here ya go, *two* of them:


1,494 posted on 05/15/2003 9:44:13 PM PDT by Ichneumon
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To: MEGoody
The fact that scientists were involved and setting up the scenario in which to conduct the experiment kind of puts a dent in the idea that this provides any support for 'unguided' evolution.

That's because you don't understand it, to be blunt.

I've done genetic programming, and I can tell you for a fact that I didn't "guide" the process. In fact, I was sleeping when it came up with its results.

And no, "setting up the scenario" doesn't make the results "guided", any more than purposely putting a bucket in your back yard "guides" the rain to land in it.

Come back when you know enough about the topic to have something even approaching an informed opinion.

1,495 posted on 05/15/2003 9:46:56 PM PDT by Ichneumon
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To: gore3000
[Trollish Behavior #9:]

Seems that is the new all purpose insult used by evolutionists at anyone who dares to debate them.

No, it's only used against those who, through their repeated evasive dancing and seemingly purposefully antagonistic posts, do indeed appear to be trolling.

Like, for example, when you yourself dump a great load of inflammatory and transparently false nonsense such as:

Now it seems to me that it is the evolutionists, who insult in every post, refuse to answer questions, refuse to address the facts presented to them, refuse to back up their assertions, and gang up on opponents that are the true trolls of these threads.

Yeah. Right. Sure.

Don't you have any more useful hobbies?

1,496 posted on 05/15/2003 9:50:11 PM PDT by Ichneumon
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To: AndrewC
[You earlier declared that you weren't going to accept my statements because you hadn't seen a "chart" or "numbers" demonstrating the superiority of the new circuit. Now that they've been given to you, and they do indeed support my statements, you simply retreat to repeatedly (and emptily) stamping your feet and repeating that my statements "are still hanging".]

No you didn't.

No "I" didn't, *what*? I didn't claim I *had* done anyting in the above discription. You made the request, someone else filled it, you blew it off. All I did was watch.

Trollish Behavior #15: Making weird non sequiturs to further confuse the discussion.

I have shown you that the circuit is not the one we have been talking about.

Trollish Behavior #16: Hairsplitting. So? The other, more documented circuit is still an example to be discussed, i.e. an evolutionary evolved circuit which exceeds the performance of the best human-designed one. And yet, rather than engage in a discussion about *that* one, you keep playing, "but it's not the same as the *first* one that was shown in a picture here, so I don't gotta talk about the other one, either..."

And, in anycase, I do not accept a paper only "assertion" (simulation) no more than I accepted your posted assertions.

Trollish Behavior 17: Nitpicking. Mathematical analysis of electronic circuits is good enough for human designers and the patent office, but it's not good enough for Andrew, who won't even discuss the implications of a circuit unless it can be "proven" that the hardware performance will equal the results of well-accepted industry-standard circuit simulators.

The rest of your garbage is not worthy of more than a glance.

Trollish Behavior #18: ...speaks for itself.

The SciAm article itself on the original evolved circuit pointed out The evolved circuit is clearly more complicated but also contains redundant parts, such as the purple transistor, that contribute nothing to its functioning.. The mentioned part is clearly unterminated.

Trollish Behavior #19: Nitpicking again.

Trollish Behavoir #20: Andrew's pretending that he wasn't specifically challenged to demonstrate that the "problem" he lists is actually as big a "problem" as he implies (i.e., one big enough to change the results in any meaningful way). That challenge again, lest he forget:

That's a nice speech, but you have failed to in any way demonstrate that the circuit in question rises to the level of having "unnecessary transistors floating around" (ooh, nicely specific, *cough*) to the point where it will "affect circuit performance" (another marvelously vague claim) at "high frequencies" (*how* high?) enough that it will, you vaguely imply, defeat the performance claimed by the authors. Stop playing word games, Troll. Demonstrate your implication, or admit you're just waving your hands. In your own words, this implication (it doesn't even rise to the level of a "claim") is still "hanging".

Trollish Behavior #21: Failing to respond to the challenge that he support his "it's important, really, I swear it" implication.

Trollish Behavior #22: Simply repeating his original unsupported gripe as if that somehow strengthens it in any way.

Solder 2 diodes back-to-back and see if you get a transistor.

Trollish Behavior #23: Twisting my words into a straw man version. I was speaking of, a transistor being internally constructed of "back-to-back diodes" (i.e., in a continuous mass of semiconductor), which is different from your new nonsense about "soldering" the leads of two diodes togther in series.

Troll yourself.

Trollish Behavior #24, playing "I know you are but what am I?"

Got anything better to add to the conversation? Oh, I know, how about actually addressing the implications of the research results instead of nit-picking every wild red herring you can think of as excuses for why you shouldn't have to?

1,497 posted on 05/15/2003 10:29:57 PM PDT by Ichneumon
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To: AndrewC
Second, you have no problems jumping to conclusions:
The researchers appear to have topped their prior "personal best" and produced an even better circuit, which they presented in their later paper.
As I've already pointed out, I didn't "jump" to what I thought was a "conclusion", I specifically labeled it as a speculation (thus the word "appear", as most children would have noticed).

However, contrary to Andrew's snideness, it turns out that my speculation was a good one after all. I emailed the authors of the articles in question (gee, why didn't anyone else think of that?), and asked them about the differing circuits in the two articles. Although he's in the midst of traveling at the current time, Matt Streeter was still kind enough to email me back. On that question, he responded:

We definitely ran the cubic problem twice and got different results, and some of the earlier publications have the earlier result. [...] The SciAm article I believe has the latest one, which is better (I believe about twice the accuracy of the patented circuit on our fitness cases, vs. comparable accuracy for the earlier result).
So there you have it.

As for your unsupported implication that they had only used 2N3904 transistors in the high-frequency cubic function generator circuit, his reply is as follows:

We ran the cubic problem both with 2N3904/2N3906 and with higher-frequency transistors. I believe we got similar accuracy in both cases.
Gosh, Andrew, the researchers were way ahead of you. Who'da thunk it? And it's not surprising that they got similar accuracy in both cases, since while the 2N3904 family of transisters is not recommended for amplifier use over 100MhZ, the same stat sheet you referred to earlier showed a chart of its frequency response, and it was shown as still pretty linear up into the gigahertz range.
1,498 posted on 05/15/2003 10:49:11 PM PDT by Ichneumon
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To: gore3000
Since even the slightest disadvantage will destroy a change,

i.e., bad mutations get weeded out.

and it takes numerous changes to destroy a species,

Which won't happen because they'll get weeded out before sufficiently "numerous" bad mutations can accumulate across the whole population and "destroy" the entire species (what is this, an Irwin Allen movie?)

it is impossible for all of them to be beneficial,

They don't "all" need to be.

hence transformation of one species into another is impossible

Flawed premises, flawed conclusion.

Needs work. A whole lot of work.

1,499 posted on 05/15/2003 10:53:56 PM PDT by Ichneumon
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To: Ichneumon
I didn't claim I *had* done anyting in the above discription.

You have not done much of "anyting"[sic] but blather on about trolling. To top it all off, when I provide the evidence that completely bury your replies you call it nit-picking. Hilarious. Even more hilarious is your weaseling after accusing me of doing such.

First I say a transistor is in a sense two diodes back-to-back in response to your implication that I lied about knowing that a transistor could be used as a diode. I also provided the evidence that I knew that use of a transistor. You continue your attempt at a red herring and Ad Hominem thusly --Not only "in a sense", Troll, but in actuality.. Then after I call you on that by the using the example of soldering 2 diodes back-to-back (an actuality), you produce this Twisting my words into a straw man version. I was speaking of, a transistor being internally constructed of "back-to-back diodes" (i.e., in a continuous mass of semiconductor), which is different from your new nonsense about "soldering" the leads of two diodes togther in series.. Do you know what in a sense means? What a Maroon you are.

You made hyperbolic assertions. You did not provide evidence backing up those assertions. Your name-calling, red herring distractions indicate your complete lack of substance.

1,500 posted on 05/15/2003 11:25:24 PM PDT by AndrewC
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