[Domestic Church]

"Of course, that may be because the fatal results of FIP have virtually eliminated the susceptible part of the population."

That's exactly what is about to happen with SARS. Those of us genetically at risk will be wiped out.

[Domestic Church]

"Distribution of a genetic polymorphism (variant R131/H131 to be specific) of the Fcgamma receptor (CD32) may have implications for disease susceptibility if cirulating IgG2 is involved. It turns out that the spike glycoprotein of some coronaviruses might in fact have such activity.

The H131/R131 polymorphism is known to be an important outcome predictor in other diseases like bacterial respiratory infections, meningococcal infection, malaria, Dengue Hemorrhagic Fever, SLE, and Kaposi sarcoma. The H131 version has a high affinity for IgG2, while the R131 version of the receptor only binds IgG2 weakly.

More importantly, the H131 version is present in 61% of ethnic Chinese, 50% of Japanese, while only 23% of Caucasians or Asian Indians have the high affinity H131 CD32 receptor. "