[MrLeRoy]

Meanwhile all the illegal drugs begin an altered state of mind pretty close to the very beginning and unlike alcohol, there doesn't seem to be that equivalent of one glass of wine

Provide evidence for your preposterous claim.

Still waiting for evidence for your preposterous claim.

[A CA Guy]

It's common knowledge, one of the problems with even pot is it stays in the system and is easily picked up in blood test. So if someone is taking a drug test at work, they have to be clean of pot for a while and other drugs can stay for even longer times.
Alcohol on the other hand is out of the system fast, but just because it is would be no reason to abuse that either.

Still it would be best to avoid the illegal stuff and to use little of what is legal in even wine.