There was a time-release pseudoephedrine with 120 mg per tablet. It nicely shutdown my chronic nasal drainage. I was pleased with that, but failed to notice that I was putting in 21 hour days with ease. The cheap source of that time-release version went away. It was too expensive to purchase the smaller packages. I found out the hard way that stopping it cold turkey wasn't pleasant. It took 3 months to get the brick off my head while gagging on the nasal drainage that returned. I only take pseudoephedrine when necessary now. Very rarely.
That's why I stopped morphine the instant I could after more-or-less healing up from an exploded pancreas...