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US researchers develop revolutionary 'cancer-killing' pill
The Jerusalem Post ^ | August 2, 2023 | Staff

Posted on 08/07/2023 5:36:04 AM PDT by Twotone

US researchers at City of Hope have found a new way to treat cancer via a targeted chemotherapy pill that can kill solid tumors, according to a recent study.

The findings of this study were published in the peer-reviewed academic journal Cell Chemical Biology.

The drug in question, dubbed AOH1996, works by targeting a specific cancerous protein variant called a proliferating cell nuclear antigen (PCNA).

This protein is vital in DNA being able to replicate and therefore tumors being able to spread. How does AOH1996 help treat cancer?

This is where AOH1996 differs from other targeted cancer treatments. Most others tend to focus just on a single pathway. However, that method can result in the cancer mutating and becoming more resistant to treatment.

"PCNA is like a major airline terminal hub containing multiple plane gates. Data suggests PCNA is uniquely altered in cancer cells, and this fact allowed us to design a drug that targeted only the form of PCNA in cancer cells. Our cancer-killing pill is like a snowstorm that closes a key airline hub, shutting down all flights in and out only in planes carrying cancer cells," said City of Hope Prof. Linda Malkas in a statement.

"Results have been promising. AOH1996 can suppress tumor growth as a monotherapy or combination treatment in cell and animal models without resulting in toxicity. The investigational chemotherapeutic is currently in a Phase 1 clinical trial in humans at City of Hope."

In tests, AOH1996 was found to be useful in treating breast, prostate, brain, ovarian, cervical, skin, and lung cancers. It selectively kills cells by disrupting how those cells reproduce. This process is known as apoptosis and it prevents cells with damaged DNA from spreading throughout the body.

More clinical trials are slated to help test this drug for future use.

"No one has ever targeted PCNA as a therapeutic because it was viewed as 'undruggable,' but clearly City of Hope was able to develop an investigational medicine for a challenging protein target," said Long Gu, lead author of the study and an associate research professor in the Department of Molecular Diagnostics and Experimental Therapeutics at Beckman Research Institute of City of Hope.

"We discovered that PCNA is one of the potential causes of increased nucleic acid replication errors in cancer cells. Now that we know the problem area and can inhibit it, we will dig deeper to understand the process to develop more personalized, targeted cancer medicines."


TOPICS: Culture/Society; News/Current Events
KEYWORDS: aoh1996; cancer; cancercure; revolutionary
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1 posted on 08/07/2023 5:36:04 AM PDT by Twotone
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To: Twotone

ping


2 posted on 08/07/2023 5:37:21 AM PDT by dennisw (Never attribute to incompetence-stupidity, that which is adequately explained by malice)
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To: Twotone

Pretty soon the med beds will roll out and all of this will be moot. Thirty minutes in a med bed no more cancer, lupus, parkinsons, MS, etc.


3 posted on 08/07/2023 5:43:07 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Twotone

Safe & Effective ?????

Since the Democrat Party as a whole is a “Cancer”, lets test this ON THEM !!!!


4 posted on 08/07/2023 5:45:53 AM PDT by OHPatriot (Si vis pacem, para bellum)
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To: Twotone

Hopefully, it’s not false hope again.

There have been too many announcements in the past of possible vaccines or therapies or even cures in the past, and we still don’t have anything better than the chemotherapy treatments and radiation to fight canvers.

But, this one will be different. We just have to wait 10 or more years before it’s deemed useful and gets approved. Hopefully. Is it another false hope?


5 posted on 08/07/2023 6:14:26 AM PDT by adorno
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To: Georgia Girl 2

Never happen. The pharmaceutical industry is not in the business of healing. It’s in the business of keeping profits coming in by keeping people on their products.


6 posted on 08/07/2023 6:15:11 AM PDT by rarestia (“A nation which can prefer disgrace to danger is prepared for a master, and deserves one.” -Hamilton)
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To: rarestia

The med beds are already in production they aren’t a future concept. The military uses them. Why do you think the govt is ginning up the alien invasion illusion? Its to have an excuse to introduce the public to advanced technology that has been in existence for 60 years. And yes up until now suppressed because of big pharma. That is all going to change in the next 12-24 months.

Michael jaco a former and much respected SEAL team 6 member talks about dying in a firefight and being brought back in a med bed. Its not technology from outer space its technology developed by Nicolas Tesla.

Radical changes are getting ready to happen. This whole fight led by Donald Trump to kill off the deep state is to be able to usher in a whole new age of enlightenment.


7 posted on 08/07/2023 6:29:11 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Twotone

[[The drug in question, dubbed AOH1996, works by targeting a specific cancerous protein variant called a proliferating cell nuclear antigen (PCNA)...

The drug in question, dubbed AOH1996, works by targeting a specific cancerous protein variant called a proliferating cell nuclear antigen (PCNA). ..

“We discovered that PCNA is one of the potential causes of increased nucleic acid replication errors in cancer cells. Now that we know the problem area and can inhibit it, we will dig deeper to understand the process to develop more personalized, targeted cancer medicines.” ]]

DAang, now that is really zeroing in on the issue. Pray it works!

[[without resulting in toxicity. ]]

Wow! Great news if true and it works. Chemo sickness is awful!


8 posted on 08/07/2023 6:45:24 AM PDT by Bob434
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To: Georgia Girl 2

That would be fantastic.


9 posted on 08/07/2023 6:46:54 AM PDT by Bob434
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To: Georgia Girl 2

“med beds”
???


10 posted on 08/07/2023 7:45:21 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: rarestia

Exactly right. Tens of millions of “cottage industry jobs” would be lost if someone finds a “cure” for cancer. No one ever will, if Big Medical has a say in it.


11 posted on 08/07/2023 7:47:06 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: rarestia

“The pharmaceutical industry is not in the business of healing.”

They can heal and make a lot of money at the same time.

If not ‘heal’ then allowing continuation of life buying a horrendously expensive medication.


12 posted on 08/07/2023 8:01:22 AM PDT by cymbeline
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To: Carriage Hill

Yes, coming to a healing center or hospital near you soon. Its not space alien technology its Nicolas Tesla technology. There is a whole plethora of technological stuff coming our way as soon as this fight to kill off the NWO ends. Pretty soon you will just get in a med bed and it will scan your body, diagnose the problem and cure it in 30 minutes. You will be able to re-grow lost limbs and age regress.

We should have Had access to this stuff 60 years ago. The reason for all the recent space alien news is to bring the technology forward like they discovered it from aliens so people won’t start hanging them from light poles for withholding this stuff from us.


13 posted on 08/07/2023 8:06:47 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Georgia Girl 2

Sounds like “Star Trek” technology from the TV series and movies. Oddly, there are some things which have appeared that the original TV series used, that we have now.


14 posted on 08/07/2023 8:13:36 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: Georgia Girl 2

“The med beds are already in production they aren’t a future concept. The military uses them. Why do you think the govt is ginning up the alien invasion illusion? Its to have an excuse to introduce the public to advanced technology that has been in existence for 60 years. And yes up until now suppressed because of big pharma. That is all going to change in the next 12-24 months.”

Lol...I’m curious, Georgia Girl. I have refrained from asking you this question up till now, but today I just can’t resist.

Is there ever a QAnon conspiracy theory that you do NOT embrace and/or swallow “whole hog”? If so, what would that one be? Where or what is your red line or limit of acceptance on BS? I know, I know. You read it on the internet so it simply ‘must’ be twue, right?


15 posted on 08/07/2023 8:16:39 AM PDT by Danie_2023
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To: Georgia Girl 2

Is this what you’re talking about?

https://www.teslabiohealing.com/collections/butler-pa-center


16 posted on 08/07/2023 8:20:27 AM PDT by Carriage Hill (A society grows great when old men plant trees, in whose shade they know they will never sit.)
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To: Danie_2023

Well here’s my question to you. Is there any hokey made up version of the non functioning “Biden Government” in the totally abandoned govt sector of Washington DC you hear about on The fake news that you don’t believe?

I’ll bet you believe all the 1 million DC govt employees work from home. its totally normal for 90% of the govt buildings in our nations capital to be abandoned and in decay right?

Ask yourself this. If the Biden regime was really in control of things do you really believe:

1. Donald Trump would still be alive?
2. The Hunter Biden scandal would ever have surfaced?
3. The conservatives would have retaken the House?
4. Trumps executive orders would keep getting extended?


17 posted on 08/07/2023 8:37:16 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Carriage Hill

No that’s not what I’m talking about although I’m aware of it.


18 posted on 08/07/2023 8:39:50 AM PDT by Georgia Girl 2 (The only purpose of a pistol is to fight your way back to the rifle you should never have dropped)
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To: Georgia Girl 2

“We should have Had access to this stuff 60 years ago. The reason for all the recent space alien news is to bring the technology forward like they discovered it from aliens so people won’t start hanging them from light poles for withholding this stuff from us.”

Sooo.... for all of this to be true and real... the depopulation globalist elitists currently running, ruling and ruining the world... would have to be dead or gone soon... since they’re the ones that would object to this “miracle” healing tech and that would keep it from happening.

Seriously, you need to stay current with the latest QAnon “news”. Here’s a link to bring you up to date.

https://www.yahoo.com/entertainment/qanon-conspiracy-theorists-cure-120-025627687.html


19 posted on 08/07/2023 8:40:19 AM PDT by Danie_2023
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To: dennisw

Medbed

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From Wikipedia, the free encyclopedia
According to a false conspiracy theory, medbeds (an abbreviation of “medical bed” or “meditation bed”) are secret beds that can miraculously heal humans and extend life. The plausibility of such devices is pseudoscience.[1][2]

Medbed conspiracy theories often involve claims that the devices are utilized by members of a ‘deep state’ and billionaires and that the former President of the United States, John F. Kennedy, is still alive, lying on a medbed.[1] Belief in these devices is popular among QAnon influencers such as Michael Protzman, Romana Didulo, and YamatoQ.[2][3]

Various companies sell devices or access to beds that supposedly heal ailments via imaginary technologies while also including fine print on their websites disclaiming that no diagnoses, treatment, or cures are provided.[1][2]


20 posted on 08/07/2023 8:44:42 AM PDT by Pirate Ragnar (Be calm and act.)
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