Truvada can damage kidneys. Example case: a woman in New Mexico who contracted COVID in early 2020 and has been injected with the mRNA "vaccines" is having ongoing problems labeled "long COVID". She tried Paxlovid. Great results until 2 days following the last dose, then a HUGE rebound with symptoms far worse than her original COVID infections. Some weeks later, on the advice of a person who works with HIV infected people, she tried Truvada. It worked great. She improved enough to run 15 miles. Her doctor did a pre-test of her kidney function before starting the Truvada. A follow up check of kidney function showed a 30% decrease inside a two week time frame. She discontinued use of Truvada.
The lesson here is that Truvada works well, but may destroy your kidneys. It shouldn't be an OTC taken without monitoring of kidney function by a doctor.