It would be
It might be a good ticket but it is not a good idea. DeSantis ran for Governor, has done a good job and increases his chances in the future by being a two term Governor. VP is a ceremonial waste anymore. Necessary, but not a place for getting to the top spot.
He should avoid that situation that Palin got herself into by abandoning his office. He is young yet.
People are jumping to him without even bothering to look at who is backing and financially supporting him. He went to Trump in 2018, so he didn’t have other backers dying to support him. The pictures are there on DeSantis Wiki page of the Trumps and the Desantis’s.