Posted on 11/05/2021 8:40:55 AM PDT by SeekAndFind
Thursday was a rough day for Moderna shares after the company released revenue figures and FY guidance that deeply disappointed Wall Street expectations (potentially destroying the reputation of financier Steve Weiss, arguably Moderna's biggest promoter on Wall Street, in the process). But on Friday, Pfizer - Moderna's biggest rival - rubbed Moderna's nose in it by announcing a revolutionary new oral COVID antiviral similar to the Merck 'miracle pill' that won approval from UK regulators yesterday.
The news sent Pfizer's stock surging, while Moderna and Merck shares tumbled, during premarket trade. Pfizer shares were trading up 11%+:
The key takeaway from the Pfizer announcement is this: Pfizer said studies showed its COVID-19 pill reduced hospitalizations and deaths in high-risk patients by 89%. That's even higher than the 50% reduction in hospitalizations and deaths shown by the Merck pill. Again, like Merck, Pfizer said that it was no longer taking new patients in a clinical trial of the treatment "due to the overwhelming efficacy" of the drug, which it now plans to submit its findings to the FDA for emergency authorization (just like Merck is doing). Yesterday, Merck won approval for its new COVID antiviral, molnupiravir, from regulators in the UK, and it's pushing to wrack up as many EUAs as possible from regulators from all over.
Pfizer is already planning to seek approval emergency approval from the US government because, according to the numbers, its drug is even more effective than molnuiravir. According to the headline numbers, Pfizer's new antiviral is even more effective than the rival pill from Merck. Pfizer’s pill, which will be sold under the brand name Paxlovid, cut the risk of hospitalization or death by 89% when taken within three days after symptoms emerge (the number for Merck's drug was it needed to be taken within 5 days of infection).
“The results are really beyond our wildest dreams,” said Annaliesa Anderson, a Pfizer executive who led the drug’s development. She expressed hope that Paxlovid “can have a big impact on helping all our lives go back to normal again and seeing the end of the pandemic.”
It's expected the new drug will be made available in the US at least but in limited quantities at first.
Criticisms have also been made about the cost of molnupiravir, and Pfizer CEO Albert Bourla already affirmed on CNBC that a course of the drug will cost insurers or customers around $700 (though the firm says it intends to sell the drug at a "discounted" prices to "poorer countries".
Per the NYT:
The U.S. government has been in negotiations with Pfizer for enough pills for 1.7 million courses of treatment, with an additional option for 3.3 million, according to a senior administration official. That is about the same quantity that the United States has ordered from Merck. The government expects to pay about $700 per treatment course for both drugs, the official said.
Both the Pfizer and Merck pills are both geared toward patients regarded as high-risk, including those above the age of 60 or with conditions like obesity that make them more susceptible to severe consequences from COVID.
But while experts again touted the drug's safety profile, several scientists have spoken out about potential safety risks tied to molnupiravir, the Merck drug.
Another important question: what does this mean now for President Biden's increasingly coercive vaccine mandate?
A pill that isn’t even as effective as natural immunity at keeping people out of,the hospital. What does it do? Increase 6our chance of going to the hospital?
I suppose,one could look at it like: for every 1000 sick or elderly people who woild ordinarily end up in hospital if they got 5he virus, the pill cuts THEIR risk of ending up in hospital by 90%, so only,100 people woild end up in the hospital instead of the 1000
If true, that’s more effective than any vackseen. Stop the mandates now.
Popcorn facts can be serious, but not as serious as cornpop farts
RE: A pill that isn’t even as effective as natural immunity at keeping people out of,the hospital. What does it do?
Unfortunately, if you want to have Natural Immunity, you must risk being infected *AND* surviving first.
Pfizermectin.
HaHaHa! We have a winnah!
...compared to Ivermectin which works as well but costs maybe 1/100 of this new drug.
I wouldn’t trust band-aids made by that company.
The jab also was 89% effective in the Clinical Trials for hospitalizations.
1/21000 hospitalized for jab
9/21000 hospitalized with placebo.
NO THANKS Pfizer; I’ll take my chances.
Effective = 1 minus 1/9 = 89%
RELATIVE
PF-07321332 is an antiviral drug developed by Pfizer which acts as an orally active 3CL protease inhibitor.
https://en.wikipedia.org/wiki/PF-07321332
Therefore, in vitro activity of (Ivermectin) IVM can be explained by acting as an inhibitor of importin-α, dimeric 3CLpro, and Nsp9, but mainly over dimeric 3CLpro.
https://pubmed.ncbi.nlm.nih.gov/33843474/
Pfizer? Ppfffttt...
I am near the point where I will consider drug company research announcements to be as valid as those of tobacco companies.
I have thought for quite a while that a scheme like the 99% curative Rx for Hepatitis C (another small RNA virus) would eventually emerge.
This boosted protease inhibitor is very promising.
about the same level of credibility.
Pfizer faked trial data according to British Medical Journal (11.5.21)
Although threads may possibly address different issues, how can you trust anything Pfizer says?
Big Pharma Is The Largest Drug Cartel On Earth (10.10.21)
Insights welcome.
Yeah, and the chance of survival is about on par with the flu ie over 99%. And it’s mostly the severely ill and elderly that die, and even that group 8s well over 95+% safe. I’ll take my chances
It is meaningless. They have no idea why some end up in the hospital and others do not. The majority who get covid will already not end up in the hospital.
More $cience!
“...compared to Ivermectin which works as well but costs maybe 1/100 of this new drug.”
The politicians need the higher price so that there is kickback money in it for them.
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