Chris Masterjohn
So it looks like Pfizer only tested most organs for their vaccine proxy biodistribution up to 48h because it only lasted that long in the liver. But the liver had max concentrations at 8 hours whereas ovaries kept increasing up to the 48h mark.
The liver stays stable from 8 to 48 hours, but the concentration in the ovaries triples between 8 and 48 hours.
Given that difference, why would it be sensible to think it disappears from the ovaries after 48 hours just because it disappeared from the liver in that timeframe?
They expected the spike protein to be subject to proteolysis, so “it was thought that there was no need to evaluate metabolism and excretion of these components.”
So, it was the lipid delivery system containing a reporter gene that was tested and shown to accumulate in the ovaries in an increasing manner without ever testing how long it lasted. But whether mRNA or spike protein lasted that long or longer wasn’t even tested.
In blood, it peaks at 1 hour and starts dramatically declining after 4 hours.
So it disappears rapidly from blood, and modestly fast from liver.
The two tissues where there are large concentrations that keep increasing right up until the end of the study are ovaries and adrenals.
Bone marrow has much less, but also has the trend of increasing right up to the end of the study.
The only organ mentioned as being studied for toxicity is the liver.
I find it baffling that anyone can consider this adequate for ruling out long-term effects in organs. The ovaries and adrenals are of most concern to me. Bone marrow on the list.
https://twitter.com/ChrisMasterjohn/status/1408303568868843521
https://www.dropbox.com/s/v2im834kdp950cm/Pfizer_ovaries_study_in_English.pdf?dl=0
Let’s see if you hear from the pro-vaxxers on this.
Thank you for sharing the analysis.