I am confident the issue is most certainly, "some people are indeed born "homo/lesbian" and how do we responsibly regard that segment of our society?
No problem, they just need to live a chaste life. It is the sin of homosexual sex that God condemns, not specifically people who feel a same-sex attraction. While disordered, it is not a sin in and of itself.
That is certainly one of the answers on the table, but my question that you recited concerns society's behavior not the individuals.
So, let me rephrase the question with a broader context.
How should society react to a male who perhaps as the result of pre-natal abuse or just a quirk of nature, has had every reason during his thinking life to thoroughly believe he is a female?
With that I am supposing his sin, if any, is his concern and not that of society.
I noted above that I believe modern medicine can effectively address the condition. Further, if society is going to provide medical benefits that should be included.