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The emerging role of mRNA methylation in normal and pathological behavior
pubmed ^

Posted on 05/19/2021 5:19:38 PM PDT by algore

Dynamic mRNA modifications, summarized as the epitranscriptome, regulate transcript maturation, translation and decay, and thus crucially determine gene expression beyond primary transcription regulation. However, the extent of this regulation in the healthy and maladapted adult brain is poorly understood. Analyzing this novel layer of gene expression control in addition to epigenetics and posttranslational regulation of proteins will be highly relevant for understanding the molecular underpinnings of behavior and psychiatric disorders.

(Excerpt) Read more at pubmed.ncbi.nlm.nih.gov ...


TOPICS: Culture/Society; Miscellaneous
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Scientists have done some other cool stuff like:

'transfering' a memory through RNA injection

https://www.sciencedaily.com/releases/2018/05/180514151920.htm

and we know that the mRna stuff they are desperate to inject people with crosses the blood brain barrier.

Probably nothing, but fun to consider.

1 posted on 05/19/2021 5:19:38 PM PDT by algore
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To: algore

I wonder if it would work in the maladapted adult brains of the Strange-Brew-Crew mob of anti-vaxxers.


2 posted on 05/19/2021 5:25:16 PM PDT by House Atreides
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To: House Atreides

Thats funny right there


3 posted on 05/19/2021 5:26:44 PM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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To: House Atreides

I have yet to find a single anti-vaxxer on Free Republic.

There are definitely anti-mRNA-COVID-19-vaxxers.


4 posted on 05/19/2021 5:29:05 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: algore

Under-methylation is one (among many) cause of depression and doctors have given methylfolate to patients for quite some time.


5 posted on 05/19/2021 5:30:44 PM PDT by packagingguy
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To: ConservativeMind

There are lots of antivaxxers, not just anti CoVID vaccine


6 posted on 05/19/2021 5:33:43 PM PDT by gas_dr (Conditions of Socratic debate: Intelligence, Candor, and Good Will. )
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To: ConservativeMind

but there are a lot of vaxxer trolls that have been here for just over a year and only post to covid threads

they have a fellow traveler list that they reply to when they see a thread, so they can all swoop down like fat hungry birds in a fat food restaurant parking lot


7 posted on 05/19/2021 5:34:03 PM PDT by algore
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To: ConservativeMind

Then you have been hiding under a rock as I have observed dozens of “anti-vaxxers” on this forum over the years.

Most before mRNA vaccines were even known let alone being administered.


8 posted on 05/19/2021 5:43:02 PM PDT by traderrob6
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To: algore
'transfering' a memory through RNA injection

Could make a huge black market for those...

9 posted on 05/19/2021 5:43:02 PM PDT by monkeyshine (live and let live is dead)
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To: traderrob6

What vaccines were they saying shouldn’t be taken?


10 posted on 05/19/2021 5:50:01 PM PDT by ConservativeMind (Trump: Befuddling Democrats, Republicans, and the Media for the benefit of the US and all mankind.)
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To: House Atreides

I wonder if it would work in the maladapted adult brains of the Strange-Brew-Crew mob of anti-vaxxers.
*****************************************************
There would need to be an approved vaccine before you could be an anti-vaxxer. Anti-voluntary lab specimen would be a better label


11 posted on 05/19/2021 5:52:59 PM PDT by Joshua (Keep paying attention to the shiny orb!)
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To: algore

I am homozygous for the MTHFR defect and it has caused a lot of health problems.


12 posted on 05/19/2021 5:54:29 PM PDT by dixie1202
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To: ConservativeMind

i AM AGAINST GENETICLY MODIFIED FOOD SO IT IS NATURAL TO NOT WANT TO CHANGE MY mRNA


13 posted on 05/19/2021 6:00:33 PM PDT by PCPOET7 (`)
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To: algore

“fun to consider.”
Yep!

All the evidence is that these vaccines are safe.

But what will mRNA be used for in the future?
It’s to medicine almost like the the atomic breakthrough was to physics- great possibilities of Man doing good or evil with it.


14 posted on 05/19/2021 6:06:08 PM PDT by mrsmith (US MEDIA: " Every 'White' cop is a criminal! And all the 'non-white' criminals saints!")
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To: ConservativeMind

Personally, I am VERY close to being an ‘anti-vaxxer’ when it comes to the CCP-Coronavirus.

Under the ‘leadership’ of the CON-servative Premier, Jason ‘Justin’ Kenney, four preachers were arrested for not limiting their congregation to 15 and one church was confiscated. Police ‘crashed’ several church services, interrupting and taking pix of the congregation. ALL of those actions are COUNTER to our PRINCIPAL law, Canada’s Charter of Rights and Freedoms. One of those churches is meeting in secret, apparently outside, in an unknown location. Of course, the AHs at AHs (Alberta Health Services) are doing all they can to locate the service location and re-arrest the Preacher!

Now, Kenney is pushing the population to ‘get the jab’ from AHs. I do not trust that there is not some ulterior motive in his begging citizens to ‘get the jab’. Also, I am just plain ‘ornery’ about his allowing, nay, even encouraging the police and AHs to trample on our natural and CONSTITUTIONAL rights. If he wants me to ‘get the jab’, THAT is reason enough, not to. Screw you, Kenney, you dictator!


15 posted on 05/19/2021 6:15:23 PM PDT by A Formerly Proud Canadian (I once was blind but now I see... )
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To: mrsmith

Imagine a time
When it all began
In the dying days of a war
A weapon — that would settle the score
Whoever found it first
Would be sure to do their worst —
They always had before…

Imagine a man
Where it all began
A scientist pacing the floor
In each nation — always eager to explore
To build the best big stick
To turn the winning trick —


16 posted on 05/19/2021 6:30:46 PM PDT by algore
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To: mrsmith
All the evidence is that these vaccines are safe.

I disagree.

There are reports in VAERS of Anaphylaxis, Thrombosis, and deaths after vaccination.

The CDC is still "investigating" to see if there is a causal link between the vaccines and the ah "adverse" reactions. However, for the last year or more anyone with any health issues and a fairly high percentage of deaths have been attributed to covid-19 on the thinnest, even non-existent evidence. Therefore I believe it is only fair to similarly attribute adverse reactions to the covid vaccines the same way. If there was a vaccine in the room and someone died, then it should be blamed on the vaccine. That has literally been the logic used.

Seriously though, the real problem with "...all evidence..." is that there is so little of it. Only a relative few (a few tens of thousands out of a population of 329 million - statistically a rounding error) people have had a vaccine for about a year. There is no data, zero, none, nada on the long term side effects because no-one has yet had it long term. By long term, that is at least 3 to 5 years since that is the known window for some autoimmune disorders to present.

Therefore there is no basis to claim the vaccines are safe. About all that can be said is that they are not immediately fatal - except for perhaps a very small percentage of people. Their ability to prevent you from getting covid is still in question (lookup "breakthrough" cases), their ability to prevent transmission is very much in question. Their efficacy against certain strains of covid-19 is estimated all over the place - some claiming they work, others that they are nearly worthless. Their long term usefulness is in doubt, many are now saying boosters will be necessary. Gosh, no-one knows what might happen after multiple doses.

My take on it is there is no reason to assume the vaccines are safe. They were rushed through development. Rushed through minimal trials. Several of them are based on brand new technology. The FDA classifies them as experimental. The companies producing them are shielded from any liability. This is not a recipe that inspires confidence. Suppose Boeing said it designed and built a replacement for the troubled 737 MAX in 7 months based on brand new, never before used in aviation technology. (note, the 787 Dreamliner took 7 years) Boeing swears it is safe, the FAA swears it is safe but still classifies it as an experimental aircraft. If anything bad happens to you due to a design or production problem, your surviving family cannot sue Boeing. A few test pilots have flown them on sunny afternoons. Now, would you get in one and fly? Would you fly in one every single day for the rest of your life?

I view the vaccines as at least as risky as the covid-19, if not moreso - at least for my demographic.

17 posted on 05/19/2021 6:43:37 PM PDT by ThunderSleeps (Biden/Harris - illegitimate and everyone knows it.)
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To: ThunderSleeps

” reports in VAERS “= nonsense.
You can’t make any conclusion from VAERS and the site specifically warns against doing so.

But, if someone says they “I just don’t trust them.” that’s all the reason they need to refuse the shot.
That’s just good common sense.


18 posted on 05/19/2021 6:47:34 PM PDT by mrsmith (US MEDIA: " Every 'White' cop is a criminal! And all the 'non-white' criminals saints!")
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To: ConservativeMind

I clicked “replies” and saw that there were no replies to your question!


19 posted on 05/19/2021 6:51:33 PM PDT by dynoman (Objectivity is the essence of intelligence. - Marilyn vos Savant)
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To: mrsmith
All the evidence is that these vaccines are safe.

After less than one year of evidence?

That's what they said about thalidomide

20 posted on 05/19/2021 6:57:28 PM PDT by ladyjane
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