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Fooling coronavirus with new decoy protein renders it impotent
Medical Express, Northwest University ^ | Mar 31 2021 | Marla Psul

Posted on 05/01/2021 8:16:14 AM PDT by delta7

A novel decoy protein designed by Northwestern Medicine scientists fools SARS-CoV-2 by intercepting the spike of the coronavirus and rendering it impotent.

The novel protein significantly reduced lung damage and resulted in only mild symptoms in mice infected with SARS-CoV-2, while untreated animals in this model all succumbed to the infection.

"We envision this soluble ACE2 protein will attenuate the entry of coronavirus into cells in the body mainly in the respiratory system and, consequently, the serious symptoms seen in severe COVID 19," said lead investigator Dr. Daniel Batlle, a professor of medicine at Northwestern University Feinberg School of Medicine and a Northwestern Medicine physician. "We have converted a lethal disease to a milder lung disease that is fully reversible. The protein could be complimentary to other potential treatments or effective alone."

The protein is a variant of ACE2 (angiotensin converting enzyme-2), the receptor the coronavirus uses to enter and infect human cells. The modified protein intercepts the S spike of the coronavirus and fools it into binding to it rather than the real ACE2 receptor in cell membranes.

The study is the first proof of concept that a soluble human ACE2 protein is effective in vivo in a preclinical study using an appropriate animal model. The soluble ACE2 protein variant developed by Batlle and colleagues binds well to the coronavirus and has been enhanced so it's effective for days......


TOPICS: Culture/Society; Government; News/Current Events
KEYWORDS: ace2protein; chinavirus; chinavirustreatment; chinavirusvaccine; covid
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Not mentioned if it is MRNA based.....worth watching its development. Brings to mind “ Haste makes waste” in rushing to take an experimental jab......
1 posted on 05/01/2021 8:16:14 AM PDT by delta7
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To: delta7

From the article:


“While widespread vaccination is the best way to combat the COVID-19 pandemic, there will always be a need for treatment of people who were not vaccinated or for whom the vaccine was not fully effective,” Batlle said.”
...

“The next steps involve the planning of safety studies needed before applying for Investigational New Drug approval for future studies in patients with COVID-19.”

Note the words “for whom the vaccine was not fully effective”.


2 posted on 05/01/2021 8:20:07 AM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000))
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To: WildHighlander57

Relegated to the back of the bus, along with HCQ and Ivermectin, etc.

They’ll now lose their funding and begin receiving harassing phone calls in the middle of the night, such is the left and deep state...


3 posted on 05/01/2021 8:22:27 AM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: delta7
The protein could be complimentary to other potential treatments or effective alone.

complementary.

This one really bothers me.
4 posted on 05/01/2021 8:27:07 AM PDT by Deo volente ("When we see the image of a baby in the womb, we glimpse the majesty of God's creation." Pres. Trump)
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To: delta7

The new ACE2 protein bars better have chocolate flavored.


5 posted on 05/01/2021 8:27:44 AM PDT by BiglyCommentary
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To: delta7

“Get your impotency shots!”


6 posted on 05/01/2021 8:37:07 AM PDT by a fool in paradise (Lean on Joe Biden to follow Donald Trump's example and donate his annual salary to charity. )
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To: delta7

New and improved ACE2! Now prion free!


7 posted on 05/01/2021 8:45:01 AM PDT by MrBambaLaMamba (Kickbacks and graft for oligarchs, free crack and hookers for oligarch's children is infrastructure )
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To: delta7

Very interesting and novel approach.


8 posted on 05/01/2021 8:46:50 AM PDT by DannyTN
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To: delta7

Why was the Coronavirus wearing a tuxedo?

“If I’m going to be impotent, I might as well look impotent!”


9 posted on 05/01/2021 8:48:04 AM PDT by dfwgator (Endut! Hoch Hech!)
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To: Deo volente

Maybe the author meant you get it free.


10 posted on 05/01/2021 8:49:18 AM PDT by firebrand ( : ) )
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To: Deo volente

Bunch of loosers.


11 posted on 05/01/2021 8:52:09 AM PDT by gitmo (If your theology doesn't become your biography, what good is it?)
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To: delta7

Herd immunity is the only safe, reliable defense. And why they are not testing for antibody titers we do for measles, mumps, etc. is the question. If a person shows they have sufficient antibodies against covid, that is all they need. No vaccinations necessary. It’s just a blood test.


12 posted on 05/01/2021 9:06:33 AM PDT by doc maverick
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To: delta7

Sure-— bring in MORE designer Angiotensin Converting Enzyme 2 proteins to try to “fool” the spike S-proteins on the surface of the SARS-Cov19/20 CCP Wuhan coronavirus. That will help==

maybe increase Hypertension too.

This is SO out of date in needless speculation- Go back to the MedCram series on youtube— have posted the Continuing Education certified presentations there by Dr. Scheulte, pulmonologist— on the mechanism of infection (the ACE2 receptors on the surface of lung cells is sought out by the S-Spike proteins on the exterior of the Covid virus— and the “key” meets the “lock” ACE2 receptor and voila— IN comes the foreign Viral mRNA that infects the lung cell which replicates and expands spreads the virus infected cells to then die and create the template for VIRAL pneumonia converted to bacterial. Overwhelm the lungs with detritus and blockage (then cascades of failing CYTOKINE explosion— which kills the victim rapidly).

So— put MORE ACE2 protein around in the plasma to “adsorb” (the correct word) and “take up” the covid S proteins and “coat” them with the ACE2/S protein amalgam around each viral particle?

Would it not be better to use Zinc, bioflavinoids, Vit D3, Vit C and N-Acetyl Cysteine (zinc ionophore) to PREVENT any S protein from ever connecting with an ACE2 receptor-— in the first place? Which is what also HCQ and Ivermectin does-. If the potential victim is also taking a potent ACE2 Blocker for blood pressure control (Losartan, Candesartan generic names for these drugs)-— the blockage is nearly complete when added to the above.

This is all in the MedCram series, and is well known to the Marik (Eastern Virginia Medical School) protocols, and also to Johns Hopkins. Well known. And is being used by millions of people to prevent infection. vs. this continuous silly ‘well we can vaccinate— and maybe it will get the numbers down” shotgun approach.


13 posted on 05/01/2021 9:18:00 AM PDT by John S Mosby (Sic Semper Tyrannis)
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To: delta7; neverdem; ProtectOurFreedom; Mother Abigail; EBH; vetvetdoug; Smokin' Joe; Global2010; ...
I've often wondered if a virus could be filtered from the patient's blood by running it through a filter coated with the target proteins.

That might be even safer than flooding a patient's bloodstream with those proteins, it should be less apt to provoke an autoimmune response...

Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

Quarantine the sick. Protect the vulnerable. Free everyone else.

14 posted on 05/01/2021 9:21:49 AM PDT by null and void (When you put bad people in charge expect bad things to happen, often in a spectacular and sudden way)
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To: gitmo

“Bunch of loosers”

Your right about that!


15 posted on 05/01/2021 9:22:50 AM PDT by pghoilman (Earth First. We'll drill the rest of the galaxy later.)
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To: Deo volente

I get exasperated by the non-use of exacerbated...


16 posted on 05/01/2021 9:23:55 AM PDT by null and void (When you put bad people in charge expect bad things to happen, often in a spectacular and sudden way)
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To: John S Mosby
“adsorb” (the correct word)

Yup.

When I'm in doubt as to whether it's soaked up in the bulk or stuck to the surface, I default to 'sorb or 'sorbed...

17 posted on 05/01/2021 9:28:29 AM PDT by null and void (When you put bad people in charge expect bad things to happen, often in a spectacular and sudden way)
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To: MrBambaLaMamba

New and improved ACE2! Now prion free
.......
That is scary. What exactly do you mean?


18 posted on 05/01/2021 9:47:37 AM PDT by amihow (Postmodernism kills the real.)
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To: delta7

Think is pill??


19 posted on 05/01/2021 9:48:31 AM PDT by amihow (Postmodernism kills the real.)
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To: amihow

Think is pill??
—————-
No idea, but pills at least can be stopped at any time if side effects are noticed. I am reminded what my Pastor has said “ be very, very careful what you choose to have injected into your body”....there is no going back once injected....that said, I have done just fine for over a year going to church, work,vacation, shopping, visiting my 89 year old mother frequently ( she has not bought into the fear), not wearing the face diapers....and not buying into the massive, manufactured fear peddling.


20 posted on 05/01/2021 10:06:04 AM PDT by delta7
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