Posted on 01/23/2021 6:43:51 PM PST by CondoleezzaProtege
LONDON: Oxford University researchers are planning to trial a drug that has shown signs of reducing COVID-19 deaths in developing countries.The Principle trial is aiming to find a drug that works soon after virus symptoms appear in a patient, and one that is most effective during the primary stages of the illness, The Times reported.The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives, the report added.Other scientists said the drug had not been assessed properly and that the full extent of its efficacy was not yet known.“It has potential antiviral properties and anti-inflammatory properties and there have been quite a few smaller trials conducted in low and middle- income countries, showing that it speeds recovery, reduces inflammation and reduces hospitalisation,” said Chris Butler, professor of primary care at Oxford and co-chief of the Principle trial. “But there’s a gap in the data. There’s not been a really rigorous trial.”
Medicine used for parasitic worm infections Other scientists said the drug had not been assessed properly LONDON: Oxford University researchers are planning to trial a drug that has shown signs of reducing COVID-19 deaths in developing countries.
The Principle trial is aiming to find a drug that works soon after virus symptoms appear in a patient, and one that is most effective during the primary stages of the illness, The Times reported.
The trial is assessing Ivermectin, a medicine used on livestock and people who have been infected by parasitic worms, which has been hailed by some as a “wonder drug” with the potential to save thousands of lives, the report added.
Other scientists said the drug had not been assessed properly and that the full extent of its efficacy was not yet known.
“It has potential antiviral properties and anti-inflammatory properties and there have been quite a few smaller trials conducted in low and middle- income countries, showing that it speeds recovery, reduces inflammation and reduces hospitalisation,” said Chris Butler, professor of primary care at Oxford and co-chief of the Principle trial. “But there’s a gap in the data. There’s not been a really rigorous trial.”
The medicine works by blocking the entry of a protein into a cell’s nuclei, limiting the replication capacity of the virus, and initial analysis from the World Health Organization has shown promising signs.
“It could save thousands of lives a day,” said Paul Marik, from the Eastern Virginia Medical School. “The data is compelling: across Mexico, India and South America, mortality has fallen.”
Peter Horby, the Oxford University professor who helped to set up the UK’s largest COVID-19 trials, said this month the latest data was “interesting, perhaps encouraging, but not yet convincing.”
Most breakthroughs in coronavirus treatments to date work on patients who are already suffering in the later stages of the illness, but Butler and his team are hoping to find a medicine that can prevent the virus from taking hold within its host.
The trial is looking for people aged 65 and over, or those aged over 50 who have underlying health conditions, through general practitioners, online, and through the UK’s NHS Test and Trace system, The Times said.
Please join me in a day of prayer for the removal of whatever strangleholds and special interests at work in our country, currently inhibiting the research into and employment of every potential treatment for this insidious disease.
My son is a doctor at a hospital that uses Ivermectin on COVID patients when they enter the hospital. He told me that they aren’t seeing any change in outcomes when patients are given this drug. However, I don’t believe he has any experience with people using it as a prophylactic. He said the same thing about hydroxychloroquine and the z-pack back back when everyone was claiming that this was a miracle cure. At that time he was working in a New York City hospital and they were using them and they were not getting any positive results.
If they're not getting the drugs until they're sick enough to be admitted it's probably too late for anything.
I have seen it work in mid to late disease until the evil empire hospital chain (one hospital in which I hold privileges) forbade any use of ivermectin. I have fought it tooth and nail under right to try, but the pharmacists at the national level refuse to allow us to dispense.
Disgusting.
I don’t know much about medicine, but I’m wondering how it is my son’s hospital is using this drug when it doesn’t seem like it has been approved for use with COVID patients.
I also don’t know just how sick you have to be to end up in the hospital with COVID. So, maybe that’s why they haven’t seen results at his hospital. They aren’t getting it early enough.
IVERMECTIN, and HCQ, protocols have been proven extremely effective against Covid when taken within 72 hrs of onset of symptoms. By the time people decide they’re so bad off that they need to go to a hospital they very likely have had symptoms for much longer than 72 hrs. If your son can provide the stats of how long people had symptoms before they showed up at his hospital, then maybe we can establish how effective their Ivermectin treatment really is.
Good point.
I try hard not to ask him too many questions because I know he’s really busy now. But, I’ll run this by him and see what he says.
I have used it in the ICU several times with some success. It is not a “miracle” in late phase disease, although I have seen it turn a couple people around. Far better than HCQ. I think early disease can be reversed by it.
“90+% of bronchiole asthma is parasitic”
I’ve been dealing with asthma for over 40 years (on and off). I’ve never thought about if it got better after a round of antibiotics.
Hmmmm.
I am a Clinical Pharmacist and now mercifully retired. I knew this a year ago as many of my fellows in medicine.
If I get covid I will treat myself with meds I have. I will not get ill.
Yes, thanks. I totally understand how busy they are. It’s just that everything I have read and heard about both Ivermectin and HCQ is that it works excellently when taken within 72 hrs of symptoms. Essentially these two drugs prevent the virus from replicating as it works into the cells, thereby reducing the viral load, so if done early enough the your body immune system won’t be overwhelmed. The virus replicates exponentially really fast once it gets inside your cells and uses the cells as a copy machine to make even more viruses to spread inside your body and quickly into lung tissue causing a cytokine storm that begins to fill up your lungs with fluid, hence the coughing and ultimate ventilator requirements.
You must be horrified to see the medical establishment essentially condemning people to death solely for political reasons. I never dreamed I would see this in this country. I came from Cuba, and even in Cuba they would never dream of doing what I am seeing in this country right now. It is utterly insane and horrible. We are governed by evil and misguided people.
Might check these studies, same website additional information there.
Ivermectin https://c19ivermectin.com/
Hydroxychloroquine https://c19study.com/ https://hcqmeta.com/
Bkmk ivermectin
Definitely agreeing with you for, once again, TRUTH to be revealed and prevail!
There’s an awful lot of circumstantial evidence that ivermectin can prevent clinical progression of COVID in a substantial majority of people.
There’s one retrospective paper that makes a strong case that it’s effective for prophylaxis as well, but it’s only one paper. Hard to say either way.
In any event, the NIH has removed it’s “recommend against” to “can’t recommend either for or against”, the same as the monoclonal antibody treatments that are not in the least controversial.
I finally broke down and got a prescription for it. I suspect that the floodgates will open up, and it’s going to suddenly be in short supply.
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