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WHO Information Notice for IVD Users 2020/05 Nucleic acid testing (NAT) technologies that use polymerase chain reaction (PCR) for detection of SARS-CoV-2(Convenient timing - and read all the next articles)
WHO ^ | 1-21-2020 | Medical product alert

Posted on 01/21/2021 1:32:02 PM PST by Vendome

Purpose of this notice: clarify information previously provided by WHO. This notice supersedes WHO Information Notice for In Vitro Diagnostic Medical Device (IVD) Users 2020/05 version 1, issued 14 December 2020.

Description of the problem: WHO requests users to follow the instructions for use (IFU) when interpreting results for specimens tested using PCR methodology.  

WHO reminds IVD users that disease prevalence alters the predictive value of test results; as disease prevalence decreases, the risk of false positive increases (2). This means that the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as prevalence decreases, irrespective of the claimed specificity.

Most PCR assays are indicated as an aid for diagnosis, therefore, health care providers must consider any result in combination with timing of sampling, specimen type, assay specifics, clinical observations, patient history, confirmed status of any contacts, and epidemiological information.

(Excerpt) Read more at who.int ...


TOPICS: Constitution/Conservatism; Crime/Corruption; Culture/Society; News/Current Events
KEYWORDS: go; let; my; people

1 posted on 01/21/2021 1:32:02 PM PST by Vendome
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To: Vendome

What does this mean?


2 posted on 01/21/2021 1:40:06 PM PST by Jan_Sobieski (Sanctification)
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To: Vendome

Who is that a picture of in the meme?


3 posted on 01/21/2021 1:44:22 PM PST by Robert DeLong
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To: Jan_Sobieski

“WHO reminds IVD users that disease prevalence alters the predictive value of test results; as disease prevalence decreases, the risk of false positive increases (2). This means that the probability that a person who has a positive result (SARS-CoV-2 detected) is truly infected with SARS-CoV-2 decreases as prevalence decreases, irrespective of the claimed specificity.”


An explanation for the explosion of positive cases driving public policy.

Coupled with valid reporting and verified fake death determinations, I call TOTAL BS on the 400k death number. I predicted early on that we could see 250-350k in total, but in reality I don’t believe for a second that we’re even close to those numbers (half, perhaps...i.e. “a bad flu season”).


4 posted on 01/21/2021 1:47:38 PM PST by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: Jan_Sobieski

It means that Biden will soon be touting that he actually DECREASED Trump’s high COVID death rate.

Wait for it.


5 posted on 01/21/2021 1:51:55 PM PST by keats5
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To: logi_cal869

They changed the reporting requirements of “Died from____ (covid) away fro how they used to do it. Worth a read::

https://mobile.twitter.com/nickpineault1/status/1316744440917250049


6 posted on 01/21/2021 2:20:02 PM PST by Basket_of_Deplorables (Convention Of States is our only hope now!)
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To: Jan_Sobieski

It means Bayes Theorem is still valid.

If a test is 90% accurate, it does not mean that IF you get a positive result, then there is a 90% chance you have the disease.

It means that IF you have the disease, there’s a 90% chance the result will be positive.

The chance you have the disease given a positive test is actually population dependent. Search on Bayes Theorem and have fun.


7 posted on 01/21/2021 2:20:13 PM PST by fruser1
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To: fruser1

Thank you


8 posted on 01/21/2021 2:22:37 PM PST by Jan_Sobieski (Sanctification)
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To: logi_cal869
https://mobile.twitter.com/nickpineault1/status/1316744440917250049/photo/1
9 posted on 01/21/2021 2:25:32 PM PST by Basket_of_Deplorables (Convention Of States is our only hope now!)
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To: Jan_Sobieski

i would say based on my understanding of pcr and virology, which comes from my lab contacts and my own background in instrument engineering, that of the number of positive results, the positive is more likely to be due to an artifact of the test (false pos) than due to the actual presense of covid19 (true pos).

it’s a very fine and confusing point the who is making, and if i’m right, it’s almost disinformation, as everyone should have a confirmation (by a different test and a different lab) before they believe any result. especially if it’s not from a ref lab with good controls, and safeguards in place. that would easily eliminate that small case.


10 posted on 01/21/2021 3:40:30 PM PST by dadfly
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To: Basket_of_Deplorables

I never saw that, only the other reports.

Thanks!


11 posted on 01/21/2021 8:40:58 PM PST by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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