That is what primaries are for. Replace them with conservatives then go all out to support the conservative replacements in the general election.
We can’t forget about what happened in 2012 with Akin and Mourdock though. Their, dare I say, extreme views, cost us control of the Senate. We can’t afford to do that in 2022. I seriously doubt conservatives are going to be in any condition to field an effective, unified national party in 2 years. We are in complete disarray right now. We’ll be lucky if we have internet privileges restored by then.