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Government asks drug regulator to 'understand the data' behind Oxford's Covid vaccine amid fears trial data was based on 'shaky science' because 'NO ONE who got the dose that had 90% success rate was aged over 55'
UK Daily ^ | 11/27/2020 | SAM BLANCHARD SENIOR HEALTH REPORTER

Posted on 11/27/2020 5:10:25 PM PST by aimhigh

Health Secretary Matt Hancock has asked the UK's drugs regulator to 'understand the data' coming out of Oxford University's coronavirus vaccine trial amid a row over the science behind the jab's promising results. Officials last night asked the Medicines and Healthcare products Regulatory Agency (MHRA) to consider giving emergency approval for the jab, so that it could be given out from next month if it is deemed safe and effective.

It comes after confusing trial results from Oxford found under-55s accidentally given too little of the vaccine actually had better protection from coronavirus than those who got the full doses, making it unclear how effective the vaccine really is.

Oxford's trial results this week suggested the vaccine is somewhere between 62 and 90 per cent effective, depending on the dosage people are given.

The jab turned out to be most effective among 2,741 volunteers accidentally only given a half-dose the first time they had the injection, followed by a full dose. But none of those were over 55, according to reports, meaning they didn't represent the vulnerable group who will rely on the vaccine in the real world.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: News/Current Events
KEYWORDS: covid; vaccine
So, what is the death rate for those aged 55 and younger? If it is already 10% or less, then the vaccine does nothing.
1 posted on 11/27/2020 5:10:25 PM PST by aimhigh
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To: aimhigh

Because they don’t plan on giving it to anyone over 55.


2 posted on 11/27/2020 5:11:45 PM PST by gov_bean_ counter (Potemkin Joe - Everything about him is fake)
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To: gov_bean_ counter

I dont trust the govt period on this crap

They have a deathwish for both the unborn and the elderly.


3 posted on 11/27/2020 5:18:03 PM PST by Secret Agent Man (Gone Galt; Not Averse to Going Bronson.)
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To: aimhigh

BoJo is seriously incompetent. Trump’s WWE-style kayfabe conceals a mind that focuses, laser-like, on his priorities. We may agree or disagree about those priorities, but he makes sure they get done. He wanted serious, but non-violent, drug felons released early. That’s done. He wanted vacancies in the courts filled. That’s done. He was late to the party on the wall, but that’s ongoing, despite judicial and legislative pushback. And the cherry on the cake, his crowning achievement, the vaccine - that’s done.


4 posted on 11/27/2020 5:19:34 PM PST by Zhang Fei (My dad had a Delta 88. That was a car. It was like driving your living room.)
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To: aimhigh

I posted something from a retired pediatrician. I can’t give you the specifics. The math calculation showed that you had to have X amount of people to find one this helped

He was negative about the vaccine. Dont remember which one.


5 posted on 11/27/2020 5:24:31 PM PST by RummyChick (I blame Kushner.)
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To: aimhigh
A 90% successful vaccine rate on a cold virus bioweapon with a 99.4% survival rate.

So, you have an almost 10% better chance at living through the wild virus than you have at living through the vaccine.

Uh, no thanks.

6 posted on 11/27/2020 5:31:42 PM PST by Slyfox (Not my circus, not my monkeys )
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To: aimhigh
It comes after confusing trial results from Oxford found under-55s accidentally given too little of the vaccine actually had better protection from coronavirus than those who got the full doses, making it unclear how effective the vaccine really is.

Oxford's trial results this week suggested the vaccine is somewhere between 62 and 90 per cent effective, depending on the dosage people are given.

The jab turned out to be most effective among 2,741 volunteers accidentally only given a half-dose the first time they had the injection, followed by a full dose. But none of those were over 55, according to reports, meaning they didn't represent the vulnerable group who will rely on the vaccine in the real world.

7 posted on 11/27/2020 5:35:14 PM PST by Grampa Dave (There was never a Biden win! It was stolen from Trump and us! When, will Biden Concede?)
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To: Slyfox

And exponentially better immunity against the next thing they cook up. Bird flu, pig flu, wuhan flu.


8 posted on 11/27/2020 5:51:13 PM PST by momincombatboots (Ephesians 6... who you are really at war with)
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To: aimhigh

Survivability rate of around 99% for those 55 and under.


9 posted on 11/27/2020 6:17:43 PM PST by ransomnote (IN GOD WE TRUST)
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To: ransomnote

99.8% survive already.

Stupid to get vaccinated. What are the long term effects? UNKNOWN. google narcolepsy vacine europe. Go ahead, do it. They gave swine flu (SARS1-CoV) vaccine to a bunch of people in Europe. Over 1000 got narcolepsy from it.

Permanent narcolepsy. For the rest of their lives, they just randomly fall asleep. No cure. Can’t be fixed. From the SARS1-CoV vaccine.

This is SARS2-CoV. Notice anything?


10 posted on 11/27/2020 6:37:52 PM PST by Basket_of_Deplorables (This is all a Soros funded communist insurrection! )
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To: Slyfox; aimhigh

You dont get it. Your examples show you don’t understand what the percentage effectiveness means.

The people setting up the trial randomly assign volunteers to two equal sized groups One half gets a placebo, such as a shot of saline. The other half gets the vaccine you are testing. It is double blind, meaning the patients and even the doctors directly treating them don’t know which patients get vaccine. For concreteness of this example, lets say there are 1000 volunteers. 500 get vaccine, 500 get placebo.

They stop when a certain number of patients get sick. They dont know who got what. Then they unblind. For illustration, lets say they stop when 55 people get COVID. Lets say of the 55 people who got it, it turns out 5 got the vaccine, and 50 didn’t. Then those who got vaccine had only 10% the rate of infection of the controls. The vaccine group had 5/500 or 1%, The controls had 50/500 or 10%, or ten times the rate of infection.

So, the vaccine reduced infections from 10% to 1%. It stopped 90% or 45/50 ( 9% of 10%) of the cases that would have occurred. That is what they would describe the vaccine as 90% effective. 90% less than the placebo ( untreated) group.


11 posted on 11/27/2020 6:52:49 PM PST by takebackaustin
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To: takebackaustin
So, the vaccine reduced infections from 10% to 1%. It stopped 90% or 45/50 ( 9% of 10%) of the cases that would have occurred. That is what they would describe the vaccine as 90% effective. 90% less than the placebo ( untreated) group.

It did NOT reduce “infections”, it reduced “disease”. Disease = illness from the infection, not the infection itself.

12 posted on 11/27/2020 7:00:26 PM PST by Shethink13
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To: Shethink13

Thanks.


13 posted on 11/27/2020 7:28:08 PM PST by takebackaustin
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To: takebackaustin

Thanks for the clarification.


14 posted on 11/27/2020 7:51:43 PM PST by aimhigh (THIS is His commandment . . . . 1 John 3:23)
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To: aimhigh

So, what is the death rate for those aged 55 and younger? If it is already 10% or less, then the vaccine does nothing.


Were they measure death primarily? Or infection?

You don’t want to be giving folks outside of the tested-for range the vaccine, but in theory it could still be useful if it gave those under 55 immunity - at least as a stopgap. I’m not sure that it is the most effective way to do it, but it is a plausible strategy.

One might also want to allow those who won’t die from COVID to be exposed to it rather than exposing the vulnerable.

That said, I doubt that is what was intended.


15 posted on 11/27/2020 8:14:38 PM PST by lepton ("It is useless to attempt to reason a man out of a thing he was never reasoned into"--Jonathan Swift)
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To: aimhigh

Re: So, what is the death rate for those aged 55 and younger?

For healthy persons under age 50, the COVID-19 fatality rate is essentially zero.

Under age 20 - 3 deaths per 100,000

Age 20 to 49 - 2 deaths per 10,000

https://www.cdc.gov/coronavirus/2019-ncov/hcp/planning-scenarios.html


16 posted on 11/27/2020 9:48:38 PM PST by zeestephen
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To: Secret Agent Man

They have already indoctrinated the young they need to eliminate the elderly because they represent the past and the regulate the unborn through abortion, population control. NWO agenda 21 stuff that was called a conspiracy theory. As nutty as he was Alex Jones is smiling


17 posted on 11/28/2020 3:25:15 AM PST by ronnie raygun ( Massive mistakes are made by arrogant fools; massive evils are committed by evil people.")
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To: sauropod

Blmk


18 posted on 11/28/2020 4:52:30 AM PST by sauropod (Let them eat kale. I will not comply. Sic semper evello mortem tyrannis. This is how Democracy dies.)
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To: aimhigh

Maybe they opted to not test it on the high-risk group because they were ... high risk.
Makes sense to test something on some more resilient populations before moving to those with weaker defenses in case something goes wrong.


19 posted on 11/28/2020 5:53:07 AM PST by trebb (Don't howl about illegal leeches, or Trump in general, while not donating to FR - it's hypocritical.)
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To: gov_bean_ counter

This Oxford data is pure BS. You are not allowed to change the recommended dosage after the trial is over...because one of your contractors screwed up...and your posh Oxford scientists didn’t bother to check the dosages. How slipshod can you get?

Maybe in the UK when the alternative is a rigorously tested vaccine from elsewhere.


20 posted on 11/28/2020 8:39:00 PM PST by RossA
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