Scientists raise concern over Hydroxychloroquine study by Lancet that led to the W.H.O suspending clinical trials

AFP via Yahoo News ^ | 05/29/2020 | Kelly MACNAMARA

[SeekAndFind]

Paris (AFP) - Dozens of scientists have raised concerns over a large-scale study of hydroxychloroquine and chloroquine published in the Lancet that led to the World Health Organization suspending clinical trials of the anti-viral drugs as a potential treatment for COVID-19.

Hydroxychloroquine, normally used to treat arthritis, has become one of the most high profile drugs being tested for use against the new coronavirus.

This is partly because of comments by public figures including US President Donald Trump, who announced this month he was taking the drug as a preventative measure.

In research published in the Lancet on May 22, Mandeep Mehra of the Brigham and Women's Hospital in the US looked at records from 96,000 patients in hundreds of hospitals between December and April and compared those who received treatment with a control group.

The study concluded that treatment with hydroxychloroquine and chloroquine, an anti-malarial, showed no benefit and even increased the likelihood of them dying in hospital.

Both drugs can produce potentially serious side effects, particularly heart arrhythmia.

The research published in the Lancet medical journal followed numerous smaller studies that suggested hydroxychloroquine is ineffective in treating COVID-19 and may even be more dangerous than doing nothing.

Within days the WHO temporarily suspended use of the drugs in its Solidarity Trial, which has seen hundreds of hospitals across several countries enrol patients to test possible treatments for COVID-19.

"This impact has led many researchers around the world to scrutinise in detail the publication in question," said the open letter in response to the study, which was signed by a number of prominent scientists and published Thursday.

[Skywise]

I wonder if buzzfeed will post an article investigating that.

[GnuThere]

Nothing suspicious here!
/s

[SeekAndFind]

OBJECTIONS RAISED BY SCIENTISTS TO THE LANCET STUDY:

* One of the main concerns was a lack of information about the countries and hospitals that contributed to the data, which was provided by Chicago-based healthcare data analytics firm Surgisphere.

* The authors also list “implausible” ratios of use of the drugs in some continents and discrepancies in the data for Australia, where they said there were more deaths recorded in the hospitals covered by the study than official figures for the entire country.

* “Surgisphere (the data company) have since stated this was an error of classification of one hospital from Asia. This indicates the need for further error checking throughout the database,”

SIGNATORIES TO THE LETTER EXPRESSING CONCERN:

Clinicians, epidemiologists and other researchers from around the world, from Harvard to Imperial College London.

[SeekAndFind]

OBJECTIONS RAISED BY SCIENTISTS TO THE LANCET STUDY:

* One of the main concerns was a lack of information about the countries and hospitals that contributed to the data, which was provided by Chicago-based healthcare data analytics firm Surgisphere.

* The authors also list “implausible” ratios of use of the drugs in some continents and discrepancies in the data for Australia, where they said there were more deaths recorded in the hospitals covered by the study than official figures for the entire country.

* “Surgisphere (the data company) have since stated this was an error of classification of one hospital from Asia. This indicates the need for further error checking throughout the database,”

SIGNATORIES TO THE LETTER EXPRESSING CONCERN:

Clinicians, epidemiologists and other researchers from around the world, from Harvard to Imperial College London.

[Safrguns]

Someone is lying... too many reports out there of successful results close to 100%

[stylin19a]

I’m still waiting to see how many lupus patients caught COVID-19...

[SeekAndFind]

See also this report:

Covid-19 study on hydroxychloroquine use questioned by 120 researchers and medical professionals

SOME PROBLEMS WITH THE STUDY:

* the Australian data in the study, published last week, did not reconcile with health department records or databases.

* Questions about the paper’s statistical modelling were also raised by Columbia University in the US

* further questions have been raised about the Surgisphere database and the study methodology. The signatories to the open letter, directed to the Lancet and the study authors. “The authors have not adhered to standard practices in the machine learning and statistics community,” the letter states.

* There was no mention of the countries or hospitals that contributed to the data source and no acknowledgments to their contributions. A request to the authors for information on the contributing centres was denied. Data from Australia are not compatible with government reports. Surgisphere have since stated this was an error of classification of one hospital from Asia. This indicates the need for further error checking throughout the database.

* Data from Africa in the study indicates that nearly 25% of all Covid-19 cases and 40% of all deaths in the continent occurred in Surgisphere-associated hospitals which had sophisticated electronic patient data recording, and patient monitoring. “Both the numbers of cases and deaths, and the detailed data collection, seem unlikely,” the letter says.

* The letter also expressed concern about unusually small reported variances in baseline variables, interventions and outcomes between continents, despite significant differences in demographics.

[Blennos]

The Lancet study has been shown to be bogus, a fraud.

https://www.youtube.com/watch?v=IUD_wvkNhnk&feature=youtu.be

[SecAmndmt]

The medical establishment wants to see more dead bodies

[Diogenesis]

The entire World trusts Pres. Trump.

The chief author of the nonsense is from Delhi,
where by strange coincidence, yesterday, monkeys
were getting involved in this Covid-19 Atrocity.
Monkeys in India escape with COVID-19 samples after attacking lab assistant

[nhbob1]

Anyone with half a brain in their head (all liberals obviously excluded) knew this study was nothing more than a political hit job.

[timestax]

[SunkenCiv]

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[Karl Spooner]

Those monkeys ain't stupid, they know what's going on.

----------------------------------------

[henkster]

The medical establishment wants to make money for Big Pharma.

Kickbacks.

[citizen]

More political & big pharma meddling.
Lib pols want power.
Big pharma/big medical want $billions.
bttt

[TangoLimaSierra]

I’m still waiting to see how many lupus patients caught COVID-19...

That would be very interesting.

[ProtectOurFreedom]

…unusually small reported variances in baseline variables, interventions and outcomes between continents, despite significant differences in demographics.

Wow!

Sounds like they hired a bunch of global warming “scientists” to cook their numbers.

[mmichaels1970]

If it’s so dangerous, BAN IT for Lupus and RA treatments. See what they say then.