Corona Virus Daily Thread #53 COVID-19 5/23/2020

5/23/20 | Many

[riri]

Memorial Day Weekend Corona Virus Thread

[Black Agnes]

https://www.dailymail.co.uk/news/article-8402745/US-states-increases-COVID-cases-forecast-model-ups-death-toll.html

LOTS of charts/graphs in that one.

[LilFarmer]

Good resource, thanks!

[LilFarmer]

North Carolina breaks another record for reported COVID-19 hospitalizations

https://www.charlotteobserver.com/news/local/article243393266.html

[LilFarmer]

Texas has 2,000 virus patients in hospitals for first time

https://apnews.com/0f5175feee72390b360e8ac4f04f07eb

[Black Agnes]

https://journals.physiology.org/doi/full/10.1152/ajpendo.00183.2020

“Is there an impact of the COVID-19 pandemic on male fertility? The ACE2 connection”

[Black Agnes]

(not to any of you in particular)

https://www.researchgate.net/publication/340814450_Does_COVID-19_affect_male_fertility

“Does COVID-19 affect male fertility?”

[PA Engineer]

Thanks for the two links. We finished our paper and the team is now churning back and forth with it. As soon as we submit it, I’ll get you a copy. We have challenged a great deal of eminence going all the way back to 1953. MicroRNA will do that with a systems biology approach. Now we have to agree on a deadline for the other three. Feels good to be almost done with the first. Best.

[Black Agnes]

Theoretical question:

Given the data on ACE2 receptor expression in the lungs vs. geographic origin.

1.) Do you think the ACE2 expression would mirror that in other body tissues like testis?

2.) Based on the assumption that 1 is true, do you think the chicoms were trying to sterilize other asians? Or primarily non asians?

[PA Engineer]

I think there may be a third. Were they trying to sterilize their colonies in Africa? They're hedging food and other resources there for the coming minimum. They also have fantasies of a new Silk Road.

I think they accidentally released it before they perfected the ability of specific targeting. I think it will still do a great deal of damage. The entire warning about NSADs worsening outcomes appears to be have been made up. Seems as if they wanted young adults to have high fevers.

I'm certain other body systems are involved. One of our team members has perfected a specific method for monitoring infection rate in sewage. Both genomics and counts. This is superior than the MIT procedure.

They need data fast on long term sterility issues.

[blueplum]

thanks for the ping - I lost y’all

re: male fertility

what if males were treated with estrogen therapy while sick? Would it matter in a male that was 60-70plus and had low levels of everything anyway ?

One thing about CCP Virus - it’s refueling the curiosity of body systems by light years.

[Black Agnes]

Based on one of the papers, ACE2 in testis peaks sometime between 20 and 30yrs of age.

I wonder how this particular age demographic compares to the damage profile from mumps...

[Black Agnes]

There seems to be a profile of ACE2 amounts decreasing from east to west. And increasing north to south in Europe/Africa.

AFricans seem to be somewhat in the middle wrt ACE2 expression in the lungs.

[blueplum]

The article below says marked lack of fertility is about 13% in mumps. So there’s one benchmark.

(Going back to the vascular aspect of CCPVirus, lack of bloodflow or interference in O2 exchange caused by Covid would have about the same effect as compression from gland swelling in mumps).

Loss of testicular tissue is found in 30-50 percent in mumps-related orchitis. Is there similar data for CCPVirus patients?

“2010 in the “British Journal of Urology International” reports that it might involve changes in male hormones during the early stages of orchitis. The researchers also indicate that the viral infection causes swelling that can increase pressure on the sperm-producing parts of the testis. Prolonged pressure may permanently damage the tissue, leaving it incapable of sperm production. The article notes that a reduction in sperm numbers in an ejaculate occurs in about 13 percent of men who have had mumps-related orchitis. Although this may lead to difficulty fathering a child, complete infertility is extremely rare.”

https://livehealthy.chron.com/infertility-caused-mumps-1232.html

[DEPcom]

My wife has Adeniod Cystic Carcinome works off the same receptors ACE2.

She thinks I might had been infected with Covid-19 when were at Walt Disney in Feb 10th. I ran a fever for a day and half and had a dry cough for a week when we got home.

She never got sick. She is currently on Imatinib daily, we are starting to think this might protected her from Covid-19 since it suppresses ACE2.

We will be bring this up to the Cancer Doctor later this month.

[Black Agnes]

How interesting.

Keep us updated!

[DEPcom]

Just did some google research and found this. I emailed the author to let them know we are looking into this. We will meet with cancer doctor for regular check up and get antibodies test.

Are Losartan and Imatinib Effective Against SARS-CoV2 Pathogenesis?

[firebrand]

NYC hospitalizations June 7 to June 8: 15
NYC hospitalizations June 8 to June 9: 481

[firebrand]

Sorry, that last figure should be 381.

[Black Agnes]

https://www.mdpi.com/1422-0067/14/10/21071/htm

[LilFarmer]

Coronavirus hospitalizations in NC increase again — and reach another new high
BY JONATHAN M. ALEXANDER AND JONAS POPE IV
JUNE 10, 2020 12:36 PM , UPDATED 6 HOURS 16 MINUTES AGO

The North Carolina Department of Health and Human Services reported 1,011 new cases of COVID-19 Wednesday, and 24 new deaths, while the number of people hospitalized because of the virus reached a new high.

Read more here: https://www.newsobserver.com/news/coronavirus/article243425261.html#storylink=cpy