Posted on 05/06/2020 5:35:33 PM PDT by SeekAndFind
The problem with a clinical trial is that the volunteers have to agree that they might get the tested remedy or they might get sugar pills.
I’d be more than ready to take HCQ if I was diagnosed with CV19 but there is no way in hell I’d take the risk that they might give me a worthless placebo.
Any volunteers from this forum? Or would everyone agree that the clinical trials are too risky?
Propaganda. As the entire deepstate mechanism has been commanded to put down this drug.
https://www.ahajournals.org/doi/10.1161/CIRCEP.120.008662#.XrG-i8LBjDA.twitter
Results - Two hundred one patients were treated for COVID-19 with chloroquine/hydroxychloroquine. Ten patients (5.0%) received chloroquine, 191 (95.0%) received hydroxychloroquine and 119 (59.2%) also received azithromycin. The primary outcome of TdP was not observed in the entire population. Baseline QTc intervals did not differ between patients treated with chloroquine/hydroxychloroquine (monotherapy group) vs. those treated with combination group (chloroquine/hydroxychloroquine and azithromycin) (440.6 ± 24.9 ms vs. 439.9 ± 24.7 ms, p =0.834). The maximum QTc during treatment was significantly longer in the combination group vs the monotherapy group (470.4 ± 45.0 ms vs. 453.3 ± 37.0 ms, p = 0.004). Seven patients (3.5%) required discontinuation of these medications due to QTc prolongation. No arrhythmogenic deaths were reported.
Conclusions - In the largest reported cohort of COVID-19 patients to date treated with chloroquine/hydroxychloroquine {plus minus} azithromycin, no instances of TdP or arrhythmogenic death were reported. Although use of these medications resulted in QT prolongation, clinicians seldomly needed to discontinue therapy. Further study of the need for QT interval monitoring is needed before final recommendations can be made.
I think double blind studies are unethical and immoral. Hydroxychloroquine is already regarded as a safe drug and has been shown to work. This is foot dragging in the hope they can fudge the statistics to show it doesn’t work. Total b.s.
Ditto.
Double blind studies using something KNOWN to SAVE LIVES is CHOOSING to MURDER HALF of your patients.
What????
I'm aware of the crooked VA trial and it's crooked findings. Where else has it "come under fire"?
For non lethal diseases or conditions, double blind tests can be useful, but when testing it on diseases that can kill, anecdotal evidence should be sufficient to establish a pattern.
RE: Where else has it “come under fire”?
Go to one of the news search engines, say news.bing.com
Type: “Hydroxychloroquine” on the search text box and hit on the search icon. You’ll see a huge heap of articles attacking it.... EVERYDAY( with Trump’s name often alongside it ).
I won’t be signing up myself, but perhaps Jared Kushner
could be of use.
Where’s the ZINC?!
From the article:
“The drug, heavily promoted by President Donald Trump, has come under fire by many in the medical community due to side effects.”
That is the propaganda I am talking about. They have constantly pushing the narrative that this drug is extremely dangerous even though years of evidence says otherwise. Especially for short term use.
This is a great summary of the created intrigues foisted on America by the socialist left.The left knows that Hydoxy-chloroquine therapy will cure the majority of patients if administered early in the progression of the Whuan Coronabirus disease.HCQ will also act as a preventative to infection as evisenced by the paucity of Whuna virus infections in those treated with HCQ for both Lupus and arthritus. So a massive campaign has been foisted on America to denigrate HCQ itself.Its a long read, but well woth the time.
*****************************************
Pseudo-Science behind the Assault on Hydroxychloroquine
Watts Up With That? ^ | May 2, 2020 | Leo Goldstein
Posted on 2020-05-04, 6:35:00 AM by Candor7
This is a research article published as information for health care professionals and public officials, and for an open peer review. It is not medical advice.
Summary
I reviewed the scientific literature on hydroxychloroquine (HCQ), azithromycin (AZ), and their use for COVID-19. My conclusions:
HCQ-based treatments are effective in treating COVID-19, unless started too late. Studies, cited in opposition, have been misinterpreted, invalid, or worse. HCQ and AZ are some of the most tested and safest prescription drugs. Severe COVID-19 frequently causes cardiac effects, including heart arrhythmia. QTc prolonging drugs might amplify this tendency. Millions of people regularly take drugs having strong QTc prolongation effect, and neither FDA nor CDC bother to warn them. HCQ+AZ combination, probably has a mild QTc prolongation effect. Concerns over its negative effects, however minor, can be addressed by respecting contra-indications. Effectiveness of HCQ-based treatment for COVID-19 is hampered by conditions that are presented as precautions, delaying the onset of treatment. For examples, some states require that COVID-19 patients be treated with HCQ exclusively in hospital settings. The COVID-19 Treatment Panel of NIH evaded disclosure of the massive financial links of its members to Gilead Sciences, the manufacturer of a competing drug remdesivir. Among those who failed to disclose such links are 2 out of 3 of its co-chairs. Despite all the attempts by certain authorities to prevent COVID-19 treatment with HCQ and HCQ+AZ, both components are approved by FDA, and doctors can prescribe them for COVID-19. .......( see linked article in full :)
http://www.freerepublic.com/focus/f-news/3841475/posts
That’s not a slow start.
Many studies have only fifty or less.
It’s easy to find anecdotal ARTICLES attacking it. But where are the studies that review its efficacy and find it ineffective? The survey papers I’ve read focus on its benefits. The papers that find it ineffective seem to have administered HCQ without Zinc and in the late stages of the disease.
All the comprehensive protocols I’ve read show it needs to be administered as close to first symptoms as possible for maximal effectiveness.
RE: Many studies have only fifty or less.
They were expecting a thousand at least. I guess they don’t have enough cases in the state, which is good news in my book.
A double blind study is the ONLY way to determine if the drug works or not. And in no study, ever, is a patient denied care. All patients receive the "gold standard" level of care, with some receiving the test drug and others receiving a placebo.
If a proper clinical trial is not performed, how can anyone possibly know if the drug is effective?
When your life is at stake, you can’t risk getting the placebo. Give ME the damn HCQ! It works most for most. We know this already.
RE: All the comprehensive protocols I’ve read show it needs to be administered as close to first symptoms as possible for maximal effectiveness.
AS close to first symptoms AND positive test for Covid-19. It’s important because the symptoms tend to mimic the flu.
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