Best to read the article, even if all terms are not understood. This is an extraordinary substance and derivative drug.
Also in the article:
“It appears that in patients with RA who are treated with HCQ, there is a decreased likelihood of developing diabetes compared to those who never took it.
Even more impressive, RA patients taking HCQ for more than 36 consecutive months were
70% less likely to have an incident cardiovascular event than those not taking it. . .”
Families of patients who have died in states or hospitals where they were denied chloroquine should ask some hard questions. Maybe through their lawyers.
HCQ+AZ > HCQ alone.
While it demonstrated some efficacy in RA as monotherapy, HCQ has really made its name is in combination therapy. The first major publication to look at a combination therapy tested MTX+HCQ, MTX+HCQ+SSZ and MTX+SSZ in patients with established RA. While triple did the best, MTX+SSZ did worse than either combination using HCQ. There may be an explanation for this, coming from the Oncology literature. MTX needs to be actively transported into the cells to become polyglutamated, which is the active form of MTX. It turns out that SSZ inhibits this transport system, and this inhibition is counteracted by HCQ. Makes you think twice about using MTX+SSZ without HCQ, doesnt it?Reminds me of the current discussion about the "triple" regimen of HCQ + Azithromycin + Zinc.
1) Open everything up and let all who will get infected catch the virus (Sweden is trying that, it's called herd immunity; it would definitely solve the SS shortfall problem looming)2) Keep everything locked down and wait until a vaccine is proven to yield immunity (and even an effective vaccine is only about sixty percent effective in yielding immunity on an individual basis; plus vaccines have scary side effects and this one coming will have a Gates data dot for everyone who gets it side effect)
3) Make a drug cocktail like HCQ + Doxycycline + zinc supplementation available (without restriction to hospitals only), so every physician and physician's assistant can write the scripts at first sign of a symptom and open the nation up to go back to being GREAT.
Since it is the human body immune system which defeats any virus that is defeated, reducing the viral load and keeping inflammation down is the best way to give the immune system a shot at developing immunity.
Hydroxychloroquine appears to have two sides to its efficacy: a) the drug has been proven as an inflammation reducer (used in RA and Lupus, and now with covid patients to reduce their airway inflammation); b) Hydroxychloroquine is a proven ionophore, ferrying ZINC into the infected cells where ZINC works to stop the viral replication thus reducing viral load.
So which of the three ways to have immunity in a society do you think the globalist oligarchy has in mind for America? And which of the three means to immunity do you think saves people and the last great hope for humanity, America?
One question, even if it seems obvious, does HCQ do anything to prevent the antibodies/immunity from developing?
I know it works best given early and with Zinc and Z-Pak.
What does it do for rheumatology practice?
I have spoken to 2 folks treated with this drug, not that I am opposed. However my friend with Lupus stopped taking it for fear of Macular Degeneration... aka blindness. Then I stopped to think.... I had seven WWII uncles and Aunts. All of the Males ..4 served in WW II and my 2 of my Aunts died early from one unknown and one Hypertension. Every male served and had Macular before Lung Cancer, My surviving Aunt, who all served in the WACS died of Lung Cancer, was halfway towards Macular.
They were al card playing Smokers, however.
I am not quite sure, at this point, what to think.