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How does coronavirus kill? Clinicians trace a ferocious rampage through the body, from brain to toes
Science Magazine ^ | Apr. 17, 2020 , 6:45 P | By Meredith Wadman, Jennifer Couzin-Frankel, Jocelyn Kaiser, Catherine Matacic

Posted on 04/17/2020 7:29:29 PM PDT by Lazamataz

On rounds in a 20-bed intensive care unit (ICU) one recent day, physician Joshua Denson assessed two patients with seizures, many respiratory failure and others whose kidneys were on a dangerous downhill slide. Days earlier, his rounds had been interrupted as his team tried, and failed, to resuscitate a young woman whose heart had stopped. All shared one thing, says Denson, a pulmonary and critical care physician at Tulane University. “They are all COVID positive.”

As the number of confirmed cases of COVID-19 surges past 2.2 million globally and deaths surpass 150,000, clinicians and pathologists are struggling to understand the damage wrought by the coronavirus as it tears through the body. They are realizing that although the lungs are ground zero, its reach can extend to many organs including the heart and blood vessels, kidneys, gut, and brain.

“[The disease] can attack almost anything in the body with devastating consequences,” says cardiologist Harlan Krumholz, “Its ferocity is breathtaking and humbling.”

Understanding the rampage could help the doctors on the front lines treat the fraction of infected people who become desperately and sometimes mysteriously ill. Does a dangerous, newly observed tendency to blood clotting transform some mild cases into life-threatening emergencies? Is an overzealous immune response behind the worst cases, suggesting treatment with immune-suppressing drugs could help? What explains the startlingly low blood oxygen that some physicians are reporting in patients who nonetheless are not gasping for breath? ...

What follows is a snapshot of the fast-evolving understanding of how the virus attacks cells around the body, especially in the roughly 5% of patients who become critically ill. Despite the more than 1000 papers now spilling into journals and onto preprint servers every week, a clear picture is elusive, as the virus acts like no microbe humanity has ever seen. ....

(Excerpt) Read more at sciencemag.org ...


TOPICS: News/Current Events
KEYWORDS: bioweapon; chatforum; cv19; horror; timeline
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To: Lazamataz

Have you ever read descriptions of how those killed by the Spanish Flu died?


21 posted on 04/17/2020 7:53:19 PM PDT by SoCal Pubbie
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To: SoCal Pubbie
Have you ever read descriptions of how those killed by the Spanish Flu died?

I have. Hideous.

22 posted on 04/17/2020 7:55:57 PM PDT by Lazamataz (China got this virus right off the bat.)
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To: Lazamataz

Looks like that Red Chinese bio-lab had some talented psychopaths working in it.


23 posted on 04/17/2020 7:56:27 PM PDT by BenLurkin (The above is not a statement of fact. It is either opinion or satire. Or both.)
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To: Black Agnes

Ping.


24 posted on 04/17/2020 7:57:22 PM PDT by Jane Long (Praise God, from whom ALL blessings flow.)
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To: BenLurkin
Looks like that Red Chinese bio-lab had some talented psychopaths working in it.

Can't wait to see what they cook up next.

25 posted on 04/17/2020 7:57:40 PM PDT by Lazamataz (China got this virus right off the bat.)
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To: Lazamataz

Where’s the controlled study?

Oh. They’re using anecdotal evidence to form opinions, the way all doctors always have. Every day.


26 posted on 04/17/2020 7:58:26 PM PDT by reasonisfaith (What are the implications if the Resurrection of Christ is a true event in history?)
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To: reasonisfaith

Is the accurate description of what a doctor saw, an opinion? Or is it, instead, observation?


27 posted on 04/17/2020 8:00:57 PM PDT by Lazamataz (China got this virus right off the bat.)
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To: Secret Agent Man

28 posted on 04/17/2020 8:04:11 PM PDT by Fiddlstix (Warning! This Is A Subliminal Tagline! Read it at your own risk!(Presented by TagLines R US))
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To: Vermont Lt
It sounds like more of a nerve agent. Scary stuff.

Sounds like something developed in a lab and biological weapons we were warned about in NBC training in the military.

It was also common that enemies understood that a NBC attack would lead to massive retaliation. Nobody is afraid of retaliation from America anymore.

29 posted on 04/17/2020 8:04:47 PM PDT by shanover (...To disarm the people is the best and most effectual way to enslave them.-S.Adams)
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To: Lazamataz
To put a face on the virus, rather than the cartoonish, generic spike-ball images everyone associates with this virus, try this one with thousands of virons attacking a single, dying cell.

Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample.

30 posted on 04/17/2020 8:05:23 PM PDT by ETCM
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To: Lazamataz

We need to carpet China with neutron bombs and throw the keys to the Uighars on the way out.


31 posted on 04/17/2020 8:07:14 PM PDT by MrBambaLaMamba (Quick don't be left out, hide in your house and join the George Soros Kill the Economy Club)
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To: Lazamataz

Then how come a good number of people who contract it have relatively mild or NO reactive symptoms? Something doesn’t jive.


32 posted on 04/17/2020 8:13:08 PM PDT by fwdude (Poverty is nearly always a mindset, which canÂ’t be cured by cash)
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To: fwdude
Then how come a good number of people who contract it have relatively mild or NO reactive symptoms? Something doesn’t jive.

Who knows. Could be anything. Even something simple like, how much CV gets into you on the first invasion. More time from a slow infection, more time to build a counterattack by your body.

But nobody really knows.

33 posted on 04/17/2020 8:15:11 PM PDT by Lazamataz (China got this virus right off the bat.)
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To: Lazamataz

What explains the startlingly low blood oxygen that some physicians are reporting in patients who nonetheless are not gasping for breath? ...
+++++
The best theory I have heard. But I haven’t finished the article yet.

This is a very big issue. Learn how it kills. For me it would be the highest priority.


34 posted on 04/17/2020 8:15:56 PM PDT by InterceptPoint (Ted, you finally endorsed.)
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To: Lazamataz; Vermont Lt; BobL; Kartographer; JRandomFreeper; Tilted Irish Kilt; Jane Long; ...
Great article.

PING!

35 posted on 04/17/2020 8:16:27 PM PDT by Tolerance Sucks Rocks (Wu Flu! (when I feel heavy metal) Wu Flu! (when I'm pins and I'm needles) Wu Flu!)
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To: Lazamataz
This is NOT influenza.
And yet, its mortality rate is still less than a strong influenza outbreak.
36 posted on 04/17/2020 8:17:52 PM PDT by Bratch (“If liberty means anything at all, it means the right to tell people what they do not want to hear.)
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To: Bratch

The fat lady ain’t sung yet.


37 posted on 04/17/2020 8:18:41 PM PDT by Lazamataz (China got this virus right off the bat.)
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To: Lazamataz

And yet, it appears that a large number of people get it and barely even know they have it. There is a lot we don’t know still.


38 posted on 04/17/2020 8:19:51 PM PDT by Opinionated Blowhard (When the people find that they can vote themselves money, that will herald the end of the republic.)
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To: Lazamataz

The witch better STHU!


39 posted on 04/17/2020 8:21:28 PM PDT by Bratch (“If liberty means anything at all, it means the right to tell people what they do not want to hear.)
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To: Lazamataz

ish’


40 posted on 04/17/2020 8:21:54 PM PDT by Java4Jay (The evils of government are directly proportional to the tolerance of the people.)
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