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These Drugs Are Helping Our Coronavirus Patients
Wall Street Journal ^ | 22 March 2020 | Jeff Colyer and Daniel Hinthorn

Posted on 03/24/2020 7:35:24 AM PDT by Sarcasm Factory

On March 9 a team of researchers in China published results showing hydroxychloroquine was effective against the 2019 coronavirus in a test tube. The authors suggested a five-day, 12-pill treatment for Covid-19: two 200-milligram tablets twice a day on the first day followed by one tablet twice a day for four more days.

A more recent French study used the drug in combination with azithromycin. Most Americans know azithromycin as the brand name Zithromax Z-Pak, prescribed for upper respiratory infections. The Z-Pak alone doesn’t appear to help fight Covid-19, and the findings of combination treatment are preliminary.

But researchers in France treated a small number of patients with both hydroxychloroquine and a Z-Pak, and 100% of them were cured by day six of treatment. Compare that with 57.1% of patients treated with hydroxychloroquine alone, and 12.5% of patients who received neither.

What’s more, most patients cleared the virus in three to six days rather than the 20 days observed in China. That reduces the time a patient can spread the virus to others. One lesson that should inform the U.S. approach: Use this treatment cocktail early, and don’t wait until a patient is on a ventilator in the intensive-care unit.

A couple of careful studies of hydroxychloroquine are in progress, but the results may take weeks or longer. Infectious-disease experts are already using hydroxychloroquine clinically with some success. With our colleague Dr. Joe Brewer in Kansas City, Mo., we are using hydroxychloroquine in two ways: to treat patients and as prophylaxis to protect health-care workers from infection. . . . As a matter of clinical practice, hydroxychloroquine should be given early to patients who test positive, and perhaps if Covid-19 is presumed—in the case of ill household contacts, for instance.

(Excerpt) Read more at wsj.com ...


TOPICS: News/Current Events
KEYWORDS: coronavirus; france; hcqzpac; instapundir; instapundit; medicine
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To: null and void

I suspect the market longs have exhausted their ammo and are quietly imbibing vast quantities of OH groups.

The market shorts on the other hand...


21 posted on 03/24/2020 9:21:36 AM PDT by Black Agnes
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To: Liz

I read somewhere in the past couple days that the range between a toxic / fatal dose and a beneficial therapeutic dose is quite small and patients have to be REAL careful about dosing. It has to be under a doctor’s care.

Three Nigerians also died with a self-administration.


22 posted on 03/24/2020 9:24:34 AM PDT by ProtectOurFreedom
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To: bitt

Great news!

bitt wrote:

“also,

Dr. Vladimir (Zev) Zelenko

Board Certified Family Practitioner

501 Rt 208, Monroe, NY 10950

845-238-0000

March 23, 2020

To all medical professionals around the world:

My name is Dr. Zev Zelenko and I practice medicine in Monroe, NY. For the last 16 years, I have cared for approximately 75% of the adult population of Kiryas Joel, which is a very close knit community of approximately 35,000 people in which the infection spread rapidly and unchecked prior to the imposition of social distancing.

As of today my team has tested approximately 200 people from this community for Covid-19, and 65% of the results have been positive. If extrapolated to the entire community, that means more than 20,000 people are infected at the present time. Of this group, I estimate that there are 1500 patients who are in the high-risk category (i.e. >60, immunocompromised, comorbidities, etc).

Given the urgency of the situation, I developed the following treatment protocol in the pre-hospital setting and have seen only positive results:

1. Any patient with shortness of breath regardless of age is treated.

2. Any patient in the high-risk category even with just mild symptoms is treated.

3. Young, healthy and low risk patients even with symptoms are not treated (unless their circumstances change and they fall into category 1 or 2).

My out-patient treatment regimen is as follows:

1. Hydroxychloroquine 200mg twice a day for 5 days

2. Azithromycin 500mg once a day for 5 days

3. Zinc sulfate 220mg once a day for 5 days

The rationale for my treatment plan is as follows. I combined the data available from China and South Korea with the recent study published from France (sites available on request). We know that hydroxychloroquine helps Zinc enter the cell. We know that Zinc slows viral replication within the cell. Regarding the use of azithromycin, I postulate it prevents secondary bacterial infections. These three drugs are well known and usually well tolerated, hence the risk to the patient is low.

Since last Thursday, my team has treated approximately 350 patients in Kiryas Joel and another 150 patients in other areas of New York with the above regimen.

Of this group and the information provided to me by affiliated medical teams, we have had ZERO deaths, ZERO hospitalizations, and ZERO intubations. In addition, I have not heard of any negative side effects other than approximately 10% of patients with temporary nausea and diarrhea.

In sum, my urgent recommendation is to initiate treatment in the outpatient setting as soon as possible in accordance with the above. Based on my direct experience, it prevents acute respiratory distress syndrome (ARDS), prevents the need for hospitalization and saves lives.

With much respect,

Dr. Zev Zelenko

cc: President Donald J. Trump; Mr. Mark Meadows, Chief of Staff


23 posted on 03/24/2020 9:25:11 AM PDT by WildHighlander57 ((WildHighlander57 returning after lurking since 2000)
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To: Jim Noble

This guy is talking prophylaxis.

Shifting subjects slightly, the amount of #TDS I’ve seen on HCQ + ZPack from Leftists is astounding. They won’t believe it’s already in use, are just blitheringly deranged about the whole subject. It’s sad, really.


24 posted on 03/24/2020 9:27:36 AM PDT by FreedomPoster (Islam delenda est)
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To: bitt
Dr. Zelenko's recommendations are consistent with others around the world. Thanks for posting his letter. I looked up "Kiryas Joel" and found this Wiki entry. It's a fascinating place. It sounds like a very tight-knit and closed community...
Kiryas Joel (Yiddish: קרית יואל‎, Kiryas Yoyel, often locally abbreviated as KJ) is a village within the Town of Palm Tree in Orange County, New York, United States. The majority of its residents are Yiddish-speaking Hasidic Jews who belong to the worldwide Satmar Hasidic sect.

Kiryas Joel is part of the Poughkeepsie–Newburgh– Middletown, NY Metropolitan Statistical Area as well as the larger New York–Newark–Bridgeport, NY-NJ-CT-PA Combined Statistical Area.

According to the Census Bureau's American Community Survey, Kiryas Joel has by far the youngest median age population of any municipality in the United States, and the youngest, at 13.2 years old, of any population center of over 5,000 residents in the United States. Residents of Kiryas Joel, like those of other Haredi Jewish communities, typically have large families, and this has driven rapid population growth.

According to 2008 census figures, the village has the highest poverty rate in the nation. More than two-thirds of residents live below the federal poverty line and 40% receive food stamps.

It is also the place in the United States with the highest percentage of people who reported Hungarian ancestry, as 19% of the population reported Hungarian descent in 2000.


25 posted on 03/24/2020 9:32:31 AM PDT by ProtectOurFreedom
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To: null and void

Who knows why people get that bug up their rear.

I LIKE your graphic because it is a marker that you’ve pinged that article out to everybody. I can scan an article quickly and spot your graphic; if it isn’t there, I can alert you to it.

Besides, it is very clever and fun.

Keep up the great work. It is well appreciated by many!


26 posted on 03/24/2020 9:37:07 AM PDT by ProtectOurFreedom
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To: FreedomPoster
They are truly insane. I mean that literally. There is something seriously wrong with those people. As well as Nancy Pelosi. How can someone hold a debilitating grudge for four long years? It is just weird.

This exemplifies their "thinking."


27 posted on 03/24/2020 9:40:01 AM PDT by ProtectOurFreedom
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To: Liz
Nobody can allege with a straight face that Trump told them to do something that idiotic...... “go to the pet store, buy some fish tank cleaner, and ingest it.”

The suggested dosage is about 200mg. These idiots probably took grams of it.

28 posted on 03/24/2020 9:43:52 AM PDT by TangoLimaSierra (To the Left, The Truth is Right Wing Extremism.)
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To: FreedomPoster
They won’t believe it’s already in use, are just blitheringly deranged about the whole subject. It’s sad, really.

I suspect they absolutely do know it's in use, and they absolutely do know it works in nearly 100% of cases when desperate doctors try it.

They simply WANT a huge pile of dead bodies to stand on while campaigning.

Eliminate the bad orange man by ANY means necessary is not an empty slogan to these people.

29 posted on 03/24/2020 9:47:25 AM PDT by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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To: TangoLimaSierra

They must have thought “if it’s not dangerous for a little fish, it must be safe for us.”


30 posted on 03/24/2020 9:55:14 AM PDT by Liz ( Our side has 8 trillion bullets; the other side doesn't know which bathroom to use.)
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To: null and void; FreedomPoster

He used the zinc with it.
HCQ is anti-inflammatory by itself, so no cytokine storm.
HCQ alone interferes with RdRPs.
HCQ can also work with existing zinc levels.
Zinc supplementation helps greatly however.
Z-pack shuts down secondary infection.
Zero hospitalizations!
Zero intubations!
ZERO DEATHS!

Now that the word is out on HCQ etc. my wife thinks I can relax about it. I am trying...

Thanks null and void for your work on the ping list, but wondering why somebody is jumping on you, I think it would not hurt if you would consider dropping the picture, just till this one is over. It was funny the first time, but now not so much. Now also, sometimes your comments are sarcastic, which doesn’t bother me a bit but maybe that is what is bothering the other lady. I am honestly not asking you to do this. I just felt like you are trying to be sensitive which is quite commendable in you. Your call of course.

You are such a help and blessing and I really rely on those pings so thanks!


31 posted on 03/24/2020 11:20:20 AM PDT by BDParrish ( Please correct me! I never learned anything from anybody who already agreed with me.)
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To: null and void

No, these guys I’m dealing with don’t know that at all, they’re just outraged Trump may be right and refuse to believe reality. It’s a common Leftist problem.


32 posted on 03/24/2020 11:25:38 AM PDT by FreedomPoster (Islam delenda est)
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To: bitt

Geez, if his letter isn’t already the subject of a post, make it one.

It’s not a prank, is it? Serious question.


33 posted on 03/24/2020 12:04:18 PM PDT by Norseman (Defund the Left....completely!)
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To: Sarcasm Factory; 3D-JOY; abner; Abundy; AGreatPer; Albion Wilde; AliVeritas; alisasny; ...

COVID-19 Super PING!

Git ‘er done!


34 posted on 03/24/2020 12:06:42 PM PDT by Tolerance Sucks Rocks (Wu Flu! (when I feel heavy metal) Wu Flu! (when I'm pins and I'm needles) Wu Flu!)
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To: null and void

Ummm, posting the same thing day after day, maybe? Just a guess though.


35 posted on 03/24/2020 12:06:52 PM PDT by Norseman (Defund the Left....completely!)
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To: bitt

As a C Diff. carrier, if I get this corona bug, I would certainly hope that the hospital or doctor will get me some serious pro-biotics with that cocktail. Otherwise, they will have much more to worry about than just COVID-19.

Either that, or I’ll tell them, and they’ll just reject me for the treatment (sigh).


36 posted on 03/24/2020 12:08:57 PM PDT by Tolerance Sucks Rocks (Wu Flu! (when I feel heavy metal) Wu Flu! (when I'm pins and I'm needles) Wu Flu!)
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To: FreedomPoster

Not they “They” I was referring to.

The average low information democrat voter is blissfully ignorant.

The big chunks that have floated or clawed their way to the top of the democrat politician septic tank? Not so much...


37 posted on 03/24/2020 12:10:01 PM PDT by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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To: Sarcasm Factory

Here’s another excerpt from the WSJ article:

“We had been using the protocol outlined in the research from China, but we’ve switched to the combination prescribed in the French study. Our patients appear to be showing fewer symptoms.”

But that letter, Post #13, WOW! And he’s easy to find on a search, so he’s real. I sure hope the letter is legit.


38 posted on 03/24/2020 12:11:20 PM PDT by Norseman (Defund the Left....completely!)
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To: Sarcasm Factory

Also, regarding the letter in post #13:

It’s important that he found so many (65%) already infected. That could mean that community spread is approaching its endpoint, i.e., when everyone’s been exposed, at least in some areas. After all, if 65% are infected, the remaining 35% must have already been exposed, but didn’t catch it, or are immune to it, or are severely isolated.

I do realize that he might have not been doing random testing, but still, to have that high a percentage infected...


39 posted on 03/24/2020 12:15:41 PM PDT by Norseman (Defund the Left....completely!)
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To: Silly; Norseman

Perhaps, but I haven’t gotten complaints in several days and all of the suddenly, today I started getting some.

It’s almost as if paid trolls got a new set of marching orders all of the sudden.

But that would be silly...


40 posted on 03/24/2020 12:17:27 PM PDT by null and void (By the pricking of my lungs, Something wicked this way comes ...)
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