These Drugs Are Helping Our Coronavirus Patients

Wall Street Journal ^ | 22 March 2020 | Jeff Colyer and Daniel Hinthorn

[Sarcasm Factory]

On March 9 a team of researchers in China published results showing hydroxychloroquine was effective against the 2019 coronavirus in a test tube. The authors suggested a five-day, 12-pill treatment for Covid-19: two 200-milligram tablets twice a day on the first day followed by one tablet twice a day for four more days.

A more recent French study used the drug in combination with azithromycin. Most Americans know azithromycin as the brand name Zithromax Z-Pak, prescribed for upper respiratory infections. The Z-Pak alone doesn’t appear to help fight Covid-19, and the findings of combination treatment are preliminary.

But researchers in France treated a small number of patients with both hydroxychloroquine and a Z-Pak, and 100% of them were cured by day six of treatment. Compare that with 57.1% of patients treated with hydroxychloroquine alone, and 12.5% of patients who received neither.

What’s more, most patients cleared the virus in three to six days rather than the 20 days observed in China. That reduces the time a patient can spread the virus to others. One lesson that should inform the U.S. approach: Use this treatment cocktail early, and don’t wait until a patient is on a ventilator in the intensive-care unit.

A couple of careful studies of hydroxychloroquine are in progress, but the results may take weeks or longer. Infectious-disease experts are already using hydroxychloroquine clinically with some success. With our colleague Dr. Joe Brewer in Kansas City, Mo., we are using hydroxychloroquine in two ways: to treat patients and as prophylaxis to protect health-care workers from infection. . . . As a matter of clinical practice, hydroxychloroquine should be given early to patients who test positive, and perhaps if Covid-19 is presumed—in the case of ill household contacts, for instance.

[Sarcasm Factory]

Apologies if this has already appeared at Free Republic. I just saw it myself, courtesy of Instapundit. Please see the hyperlinked Instapundit excerpt for more information than is allowed at Free Republic. I've forwarded said tidbit to family members and others who might like some insight into the growing hullabaloo over hydroxychloroquine.

[SeekAndFind]

Thanks for posting the excerpt. Unfortunately, Wall Street Journal is on a paywall. :(

[shotgun]

per news sources yesterday New York state will begin testing this regime today. Reports are they received 70,000 doses and Cuomo thanked the President for making this happen.

[Liz]

A man died and his wife became ill when they ingested chloroquine phosphate-—
-—— not a medically-prescribed drug ordered by a doctor that Trump mentioned———
but a commercially sold additive commonly used to clean fish tanks.

Nobody can allege with a straight face that Trump told them to do something that idiotic......
“go to the pet store, buy some fish tank cleaner, and ingest it.”

But the vengeful “Get Trump” media reported this as if Trump were responsible.

[wastoute]

At the same time, this death is, however tangentially, part of the epidemic. Panic behavior contributes to the chaos.

[aquila48]

“One lesson that should inform the U.S. approach: Use this treatment cocktail early, and don’t wait until a patient is on a ventilator in the intensive-care unit.”

[hardspunned]

Of course we had the independent study on the effectiveness of aquarium cleaner to stop the spread as well.

[txrefugee]

Fortunately, physicians who want patients to survive, must be using the “unproven” medicines that work, and only 14 people died of the virus in the past 24 hours. That is a great improvement in outcome. Keep praying. God listens.

[KansasGirl]

Perhaps the media should stop manufacturing so much panic.

[Pollster1]

Tonic water: 83 mg of quinine per liter. Basically, the full China-recomended dose is equivalent to 5 liters of tonic water after the first day. That’s a lot but doable. Those who say tonic water does not have enough quinine to matter are misinformed. If you assume that even a partial dose (perhaps 1-2 liters) will help the body to fight off this virus, it’s worth having some in your pantry or even on the daily menu.

[Chauncey Gardiner]

Add sublingual zinc. Thanks for posting.

[shotgun]

death is a pretty sure way to stop the body from getting infected...

[bitt]

also,

Dr. Vladimir (Zev) Zelenko

Board Certified Family Practitioner

501 Rt 208, Monroe, NY 10950

845-238-0000

March 23, 2020

To all medical professionals around the world:

My name is Dr. Zev Zelenko and I practice medicine in Monroe, NY. For the last 16 years, I have cared for approximately 75% of the adult population of Kiryas Joel, which is a very close knit community of approximately 35,000 people in which the infection spread rapidly and unchecked prior to the imposition of social distancing.

As of today my team has tested approximately 200 people from this community for Covid-19, and 65% of the results have been positive. If extrapolated to the entire community, that means more than 20,000 people are infected at the present time. Of this group, I estimate that there are 1500 patients who are in the high-risk category (i.e. >60, immunocompromised, comorbidities, etc).

Given the urgency of the situation, I developed the following treatment protocol in the pre-hospital setting and have seen only positive results:

1. Any patient with shortness of breath regardless of age is treated.

2. Any patient in the high-risk category even with just mild symptoms is treated.

3. Young, healthy and low risk patients even with symptoms are not treated (unless their circumstances change and they fall into category 1 or 2).

My out-patient treatment regimen is as follows:

1. Hydroxychloroquine 200mg twice a day for 5 days

2. Azithromycin 500mg once a day for 5 days

3. Zinc sulfate 220mg once a day for 5 days

The rationale for my treatment plan is as follows. I combined the data available from China and South Korea with the recent study published from France (sites available on request). We know that hydroxychloroquine helps Zinc enter the cell. We know that Zinc slows viral replication within the cell. Regarding the use of azithromycin, I postulate it prevents secondary bacterial infections. These three drugs are well known and usually well tolerated, hence the risk to the patient is low.

Since last Thursday, my team has treated approximately 350 patients in Kiryas Joel and another 150 patients in other areas of New York with the above regimen.

Of this group and the information provided to me by affiliated medical teams, we have had ZERO deaths, ZERO hospitalizations, and ZERO intubations. In addition, I have not heard of any negative side effects other than approximately 10% of patients with temporary nausea and diarrhea.

In sum, my urgent recommendation is to initiate treatment in the outpatient setting as soon as possible in accordance with the above. Based on my direct experience, it prevents acute respiratory distress syndrome (ARDS), prevents the need for hospitalization and saves lives.

With much respect,

Dr. Zev Zelenko

cc: President Donald J. Trump; Mr. Mark Meadows, Chief of Staff

[null and void]

SEE POST #13!

Bring Out Your Dead

Post to me or FReep mail to be on/off the Bring Out Your Dead ping list.

The purpose of the “Bring Out Your Dead” ping list (formerly the “Ebola” ping list) is very early warning of emerging pandemics, as such it has a high false positive rate.

The false positive rate was 100%.

At some point we may well have a high mortality pandemic, and likely as not the “Bring Out Your Dead” threads will miss the beginning entirely.

*sigh* Such is life, and death...

If a quarantine saves just one child's or one old fart’s life, it's worth it.

[null and void]

At the same time, this death is, however tangentially, part of the epidemic. Panic behavior contributes to the chaos.

In much the same way China counts those starved to death welded into their high-rise apartment buildings. oh wait...

[Jane Long]

Amazing!!

How soon til Fauci & Friend dispute this??

[Freee-dame]

Please stop posting this image and commentary. I skip over it as fast as I can but it is annoying to see it over and over. Imagine how useless FreeRepublic would be if lots of people posted the same image and/or commentary on multiple threads day after day. Please add something new to our discussions.

[null and void]

Please do continue skipping over it.

Thanks in advance.

[null and void]

Interesting, after days of relative quite all of the sudden I’m getting lots of flack.

Anybody happen to know why someone gets flack?

[RushIsMyTeddyBear]

They have a large Hasidic community there.