[Yes, loss of cabin air is alarmed.
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Pilots would immediately look to descend and land, and turn on the autopilot hoping to be alert enough to regain control.
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Normal flight altitude for that aircraft is 42,000 feet. Decompression would cause a blackout within a minute or less.
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Fighter jets have had this event, many did not recover.]
Certainly for the pilot to remain conscious until the plane gets below 15,000 feet. Most people should not have a problem remaining conscious below that level. -Tom