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This fertility doctor is pushing the boundaries of human reproduction, with little regulation
Washington Post ^ | May 14, 2018 | Ariana Eunjung Cha

Posted on 10/21/2018 12:25:49 PM PDT by Zhang Fei

NEW YORK — When future historians look back on the 21st century, one of the most iconic photos may be of a smiling, dark-haired man in blue scrubs protectively holding a newborn — the world’s first commercially produced “three-parent” baby.

This is John Zhang, the Chinese-born, British-educated founder and medical director of a Manhattan fertility center that is blowing up the way humans reproduce.

In 2009, Zhang helped a 49-year-old patient become the world’s oldest known woman to carry her own child. In the not-too-distant future, he says, 60-year-old women will be able to do the same.

In 2015, Zhang stunned his scientific peers by transferring a genetically “abnormal” embryo to the womb of a woman who had run out of other options. Abnormal embryos — which appear to have the wrong number of chromosomes — are almost universally considered nonviable and discarded by other fertility doctors. The woman gave birth to a healthy baby girl, prompting clinics around the world to reevaluate their policies.

But it was the three-parent baby that really put Zhang on the map. Working with a Jordanian couple who had lost six babies — two in infancy, four in miscarriages — to Leigh syndrome, a heritable neurological disorder, Zhang put to practical use a procedure that others had dared to try only on animals.

He extracted the woman’s nuclear DNA, which carries the biological material responsible for such things as physical appearance and other major traits, but not the ones that lead to Leigh disease. Then he inserted the DNA into a healthy donor egg and fertilized it with sperm from the woman’s husband. The child, a boy born in 2016, appears to be free from the disease.

“If there is a gene which causes a problem, it would be washed out through natural evolution.

(Excerpt) Read more at washingtonpost.com ...


TOPICS: Culture/Society; Extended News; Government; News/Current Events
KEYWORDS: healthcare; medicine; natalism; science
I remember the headlines from when the first test tube baby was born, back in the late 70's. For some reason, the birth of the first 3-parent baby has been greeted with a collective yawn by the media.
1 posted on 10/21/2018 12:25:49 PM PDT by Zhang Fei
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To: Zhang Fei

He extracted the woman’s nuclear DNA, which carries the biological material responsible for such things as physical appearance and other major traits, but not the ones that lead to Leigh disease. Then he inserted the DNA into a healthy donor egg and fertilized it with sperm from the woman’s husband. The child, a boy born in 2016, appears to be free from the disease.

...

It seems like this is curing disease at conception.


2 posted on 10/21/2018 12:32:03 PM PDT by Moonman62 (Give a man a fish and he'll be a Democrat. Teach a man to fish and he'll be a responsible citizen.)
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To: Moonman62

[It seems like this is curing disease at conception.]


Oddly enough, while we think of Middle Easterners as very prolific, their birth rates are rapidly going down. I suspect first cousin marriage is causing a lot of genetic problems, perhaps even more issues than encountered by Ashkenazi Jews, who at least have the benefit of diversity introduced by their ~50% Italian genes.


3 posted on 10/21/2018 12:44:53 PM PDT by Zhang Fei (They can have my pitbull when they pry his cold dead jaws off my ass.)
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To: Zhang Fei

“...Manhattan fertility center that is blowing up the way humans reproduce.”

Blowing up?

These writers are idiots.


4 posted on 10/21/2018 12:46:17 PM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: Zhang Fei

My guess is the claims made here are false.


5 posted on 10/21/2018 12:48:42 PM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: ifinnegan

[My guess is the claims made here are false.]


It’s real, to the extent that the FDA has put the kibosh on not just experimentation, but applications for experimentation. The UK has approved the procedure. The resultant pregnancies should come to term sometime soon. The Ukraine has done a couple of dozen, roughly 1/3 of which have resulted in childbirth. That’s a lot higher than the prior record of complete failure (for the couples involved) that led them to this last resort.


6 posted on 10/21/2018 12:59:39 PM PDT by Zhang Fei (They can have my pitbull when they pry his cold dead jaws off my ass.)
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To: Zhang Fei
In 2009, Zhang helped a 49-year-old patient become the world’s oldest known woman to carry her own child.

Pish-tosh. Lots of women (compared to the total population of women) naturally give birth to their own children in their 50s. The oldest verified was 57, iirc. Perhaps this means the oldest "patient" to carry her own artificially-conceived child.

7 posted on 10/21/2018 1:48:28 PM PDT by Tax-chick ("Kindness and truth shall meet." Ps. 85:10)
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To: Zhang Fei

too bad for them an 80 (?) year old lady already beat them too it -had a baby named Isaac.

Also Elizabeth was thought to be beyond child bearing years and had John.

Science is so far behind the Truth of history.


8 posted on 10/21/2018 2:09:19 PM PDT by b4me (God Bless the USA)
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To: b4me

Sarah was 90. Elizabeth was probably 40-ish because Zechariah could serve as a priest only until he was 50, and his wife would almost certainly have been several years younger than he.


9 posted on 10/21/2018 2:12:25 PM PDT by Tax-chick ("Kindness and truth shall meet." Ps. 85:10)
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