http://www.thepublicdiscourse.com/2018/03/21151/
Sex Change: Physically Impossible, Psychosocially Unhelpful, and Philosophically Misguided
by Ryan T. Anderson
Worthwhile link to read on the topic.
Cosmetic surgery and cross-sex hormones cant change us into the opposite sex. They can affect appearances. They can stunt or damage some outward expressions of our reproductive organization. But they cant transform it. They cant turn us from one sex into the other.
Scientifically speaking, transgender men are not biological men and transgender women are not biological women. The claims to the contrary are not supported by a scintilla of scientific evidence, explains Dr. Mayer.
Or, as Princeton philosopher Robert P. George put it, Changing sexes is a metaphysical impossibility because it is a biological impossibility.
You is what you is.