I think there’s something to be said for the Senate moving deliberately on legislation. I would require 60 votes for cloture on the first cloture vote, but reduce the threshold to 59 after two weeks, to 58 after two more weeks, etc., until only 50 votes are required for cloture after 20 weeks. So the most that 49 senators could do is delay a bill for five months, sort of like the House of Lords used to be able to do in the UK.
That works for me. But the way it is now is unacceptable, 41 permanently blocking the will of 59 is repugnant.