It could where ever you had a cellular signal, but 35,000 feet in the air, you generally don't have cell service. Bluetooth would be problematic, depending on where you are sitting.
The power of chemical explosives are limited by what size you can pack into them. An iPad or a working laptop the size would most likely be the size of any replaced battery the explosive is replacing. It would have to be well concealed and sealed to get around the "sniffers" that detect explosive exudations at check points. Such sniffers are not as effective as bomb detecting dogs, but I bet Muslim check points won't use dogs, given their hatred of canines. So you are starting with a very small bomb to begin with contained within a shell. Now put it in another soft container. Any explosion in the luggage would be buffered and absorbed by what was packed around it. How likely would it be that the device would be placed right next to the wall of the aircraft or a critical component? Not much. Such a small bomb would do little to no damage in the baggage compartment so the whole point of smuggling a bomb on board is useless for a terrorist's purpose, which is to do as much mayhem as possible. Vandalizing luggage is not worth the effort.
Look at the damage done with a computer bomb in the photo above. The terrorists in that incident succeeded in killing himself, the person next to him, and injuring the person in front of him. The plane depressurized, but it did not crash. People were terrorized, but a whole plane was not destroyed. It landed safely. Apparently to do that damage, he pressed his computer to the side of the plane and detonated it.
Now, picture a similar bomb buried somewhere in the pressurized baggage compartment. WHUMP! Shredded clothes. . . and some disappointed passengers when their baggage comes out of the carousel looking like it lost a ten round bout with some angry bears.
Years past the screeners made us start up the electronic gear to show it actually ran. Now they no longer do that. . . just put them through the Xray and done. Perhaps that should be re-instituted. Then iPads and other tablets could be carried. There's not much room for a bomb in a working tablet. Computers are a different story altogether. Enough room for a small battery for a short operational time and a fairly adequate bomb could be found. Look at the interior of a MacBook:
Those black blocks are the batteries. Just a single one could provide power for a short time. . . the rest could be replaced with explosive by terrorists. Not good. As a counter measure, we know exactly how much this notebook should weigh. It would be very easy to weigh it on check in. Any discrepancy and it doesn't fly. Any discrepancy on Xray and it doesn't fly. Sniff test failure and it doesn't fly. Etc. I think that's why there is a cabin ban only from these seven countries, there screening leaves a lot to be desired.