“I never stated precisely that his premise is false; rather, I stated that you won’t find such teaching in scientific circles. But surely there have been exceptions. “
Here is what you stated:
“The political narrative derives primarily from pop culture, which is formed by and includes the misleading and false narrative in the media. Certainly in the media we find widespread implication that antibiotic resistance evolves directly from human use of antibiotics.”
You say the media narrative (that antibiotic resistance evolves directly from human use of antibiotics) is misleading and false. That is Dr Wile’s premise.
With regard to proving evolution, evolution can be defined as changes in gene frequency as the result of selective pressure. Placing a culture of bacteria in a medium with an antibiotic (a strong selective pressure) results in changes in gene frequency, such that bacteria containing antibiotic resistant genes increase and those without decrease. That is evolution.
From Darwin until now the big picture of evolutionary theory paints a picture of one species changing into another.
It is an imagined and unobserved process.