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Distinct stages to chronic fatigue syndrome identified
BBC ^ | February 27, 2015 | Unattributed

Posted on 03/02/2015 11:53:10 AM PST by Seizethecarp

Distinct changes in the immune systems of patients with ME or chronic fatigue syndrome have been found, say scientists.

Increased levels of immune molecules called cytokines were found in people during the early stages of the disease, a Columbia University study reported.

The US research team, who published their findings in the journal Science Advances, tested blood samples from nearly 300 ME patients and around 350 healthy people.

They found specific patterns of immune molecules in patients who had the disease for up to three years.

These patients had higher levels of of cytokines, particularly one called interferon gamma, which has been linked to the fatigue that follows many viral infections.

Healthy patients and those who had the disease for longer than three years did not show the same pattern.

Lead author Dr Mady Hornig said this was down to the way viral infections could disrupt the immune system.

"It appears that ME/CFS patients are flush with cytokines until around the three-year mark, at which point the immune system shows evidence of exhaustion and cytokine levels drop."

This shows there are distinct stages to the disease, she said. When the cytokine response starts to settle down, the disease also appears to quieten down.

(Excerpt) Read more at bbc.com ...


TOPICS: Culture/Society
KEYWORDS: cfs; chronicfatigue; cytokines; interferongamma; mecfs; seid

1 posted on 03/02/2015 11:53:10 AM PST by Seizethecarp
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To: Fractal Trader

ping...


2 posted on 03/02/2015 11:53:45 AM PST by Seizethecarp
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To: Monkey Face

Ping.


3 posted on 03/02/2015 11:54:39 AM PST by Tax-chick (Wash, rinse, dry, put away.)
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To: Seizethecarp

The 80s called. They want their syndrome back


4 posted on 03/02/2015 11:55:37 AM PST by Kozak ("It may be dangerous to be America's enemy, but to be America's friend is fatal" Henry Kissinger)
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To: Seizethecarp

Whether cause or effect?


5 posted on 03/02/2015 12:00:08 PM PST by Uncle Miltie
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To: Kozak

Chronic pain (a slightly different but associate “syndrome”) is an excellent cover for an opiate addiction.


6 posted on 03/02/2015 12:01:15 PM PST by Uncle Miltie
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To: Seizethecarp

I know some who say they have Fibromyaligia. They have my sympathies, because many doctors still don’t recognize it as a ‘real disease’. Another sickness that many still don’t recognize as legitimate is Morgellons’ Disease, where you feel like your skin is crawling with ‘things’ that remain unseen. One of my favorite performers Joni Mitchell, used to have this bad. I believe it has gone into recession for her.


7 posted on 03/02/2015 12:02:13 PM PST by lee martell (The sa)
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To: Uncle Miltie

I’m pretty sure I had it, 20 years or so ago. It wasn’t fun. I believe it exists, despite the frequent accounts of malingerers.


8 posted on 03/02/2015 12:02:40 PM PST by Pearls Before Swine
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To: Seizethecarp

Distinct stages to chronic fatigue syndrome identified: they are
Stage 1. Work
Stage 2. More work
Stage 3. More work plus overtime, too
Stage 4. More work -don`t dream of retiring yet til you`re 90


9 posted on 03/02/2015 1:19:08 PM PST by bunkerhill7 ("The Second Amendment has no limits on firepower"-NY State Senator Kathleen A. Marchione."))))
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To: lee martell

First it was Chronic Fatigue. Then came Fibromyaligia. The new self-diagnosed disease is Chronic Lyme Disease.

I knew someone who had CFS and it went away when she went back home to visit family in Louisiana.


10 posted on 03/02/2015 1:21:26 PM PST by AppyPappy (If you are not part of the solution, there is good money to be made prolonging the problem.)
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To: Uncle Miltie
Chronic pain (a slightly different but associate “syndrome”) is an excellent cover for an opiate addiction.

It's hard to get inside somebody else's head who has chronic fatigue, or chronic pain.

Experiences which we might tend to scoff at can nevertheless be very real to others. So I can't be too judgmental about such things.

That's why, as long as such a person is not bothering anybody else, they should be free to address their medical condition as they see fit.

11 posted on 03/02/2015 1:27:28 PM PST by sargon
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To: Seizethecarp

Is it related to OFS - Obama Fatigue Syndrome?


12 posted on 03/02/2015 1:29:15 PM PST by central_va (I won't be reconstructed and I do not give a damn.)
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To: AppyPappy

Chronic Fatigue Syndrome is a joke. I know a guy who was diagnosed with it. He naps several times a day and drinks sugary sodas all day long. Duh. Sugar feeds fungus. That’s what you got son. Get off grains. Improve your diet. Improve your life.


13 posted on 03/02/2015 1:34:00 PM PST by petercooper ("How To Destroy The Country In 6 Short Years" by Barack Obama & the Democrats)
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To: petercooper

I think my example’s problem was Depression. She didn’t want to live in NC. She was on the Disability for it.


14 posted on 03/02/2015 1:45:50 PM PST by AppyPappy (If you are not part of the solution, there is good money to be made prolonging the problem.)
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To: sargon

I believe people suffer from Chronic pain but many times, doctors just dump them into something to avoid dealing with it. That’s how Chronic Lyme Disease came into being.


15 posted on 03/02/2015 1:47:25 PM PST by AppyPappy (If you are not part of the solution, there is good money to be made prolonging the problem.)
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To: bunkerhill7

Yeah, thats the one I got.


16 posted on 03/02/2015 1:53:26 PM PST by Delta 21 (Patiently waiting for the jack booted kick at my door.)
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To: Seizethecarp

I thought or think I have rheumatoid arthritis so these articles always interest me. I’ve realized that I also have other non-RA related symptoms so because of the posts here I decided to search for an immune disease system checker and voila!

http://thyroid.about.com/cs/newsinfo/l/blsymptom.htm


17 posted on 03/02/2015 3:44:20 PM PST by huldah1776
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To: AppyPappy

Don’t forget MCS.
Multiple Chemical Sensitivity.
Very popular among California Progtards in the 90s....


18 posted on 03/03/2015 1:25:39 AM PST by Kozak ("It may be dangerous to be America's enemy, but to be America's friend is fatal" Henry Kissinger)
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To: sargon

I have a friend who always has been kind of a hypochondriac. It’s not that I don’t believe she hurts its just that her pain tolerance is so very low. I have a bad case of degenerative disc disease and have dealt with it for many years. I try really hard to not let it stop me. I keep going through the pain til I just can’t anymore and then will lay down for just awhile. She on the otherhand was diagnosed with a maybe case of the same through an mri and the tech said....there may be a little pain. According to her the pain is so bad it will put her in bed for weeks.
I believe people process pain differently so I don’t scoff although I do wonder why they just want to quit living because of it. I will keep going til I absolutely cannot go anymore.


19 posted on 03/03/2015 6:54:27 AM PST by sheana
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