There is plenty of reasons for Assad to go down. That Baathist prick and Iran helped fund the Baath insurgents in Fallujah and took in al Dhouri, not to mention his regime was working on developing nukes- which Israel made clear back in 2006 when they made the bombing run into Syria.
Assad protected Christians and other minorities and he provided stability. As far as the nuke situation goes, I can’t fault countries for wanting nukes when their neighbors have them.