[Red Badger]

A slightly deflated ball would be easier to hold on to for a running back or receiver to prevent fumbles or bad catches.........

[Vigilanteman]

True, but more than offset by the advantage a passing team would have in completing long passes.

[kjam22]

A slightly deflated ball would be easier to hold on to for a running back or receiver to prevent fumbles or bad catches.........

This is correct. The difference in weight would be so minor as to not effect the game in any way. (probably not even noticable) The deflated football would need to have the pressure checked to determine.... not the weight.

You would check it with something like this...