It could happen. Convention of states could actually pass and the states could ratify the well-worded amendments necessary to cut back our grossly unconstitutional federal government, and somehow enforce its dismantling. But I believe it would be a miracle. That's OK, because I think America itself and its founding was also a miracle.
But failing that kind of miracle, States, Our Natural Second Party should also be thought about in terms of nullifying unconstitutional federal law. Arizona has just passed such a law, allowing the state to ignore a federal law if the state finds it to be unconstitutional. But a state that does this needs to be prepared for financial independence from the federal government which will almost certainly cut such a state off from federal funding. However, if that state kept its government and taxes small and allowed the free market economy to thrive, it could soon be more financially healthy than the bankrupt feds. If tiny, resource-poor Hong Kong could do it, any state can do it. It only takes bravery and willingness to fight for freedom.
Nullification is a palliative response. It doesn’t deal with the problem of concentrated power in DC.
Like you, I am not all that confident we’ll dig ourselves out of the mess it took a hundred years to get into, but I see no other option.
History will not look kindly on a people who gaffed off their duty to peacefully restore freedom.