Posted on 08/02/2014 2:04:14 AM PDT by nickcarraway
SNIP
And while Ebola is lethal, it's rare. Outbreaks are unpredictable, giving doctors few chances to test new treatments. While the current epidemic is the largest recorded, the number of people sickened by Ebola is small compared to the number killed by other diseases like malaria or dengue. Much of the funding for Ebola research is from governments that worry about the virus being used in a bioterror attack.
"It's not economically viable for any company to do this kind of research because they have stockholders to think about," said Ben Neuman, a virologist at the University of Reading in Britain.
There are about a half dozen Ebola drugs and vaccines in development, several of which have received funding from the U.S. One drug developed by the U.S. Army has shown promising results when tested in monkeys.
SNIP
(Excerpt) Read more at cbs8.com ...
I’ve been wondering, do the anti-viral drugs that were developed for treating HIV have any effect on other viruses? What would happen if, as soon as a person was diagnosed with ebola, they were started on an anti-viral cocktail along with immune boosters and blood platelets?
I’m not a doctor, but I haven’t find any reason yet why this wouldn’t help.
That drug may be the Tekmira compound mentioned here.
Now if the U.S. nurse would be smart she would claim she got Ebola when she was having an abortion, or it first presented when she took her ACA mandated birth control pills.
Then we would see all the Hollywood actors lining up to do commercials to cure this terrible disease. No money though, (they don't do the horrible “donate” thing).
O, Reggy, and a pet MOOSE while in a swamp in Kenya would even Tweet for a solution (#no-bleed-like-sweat-now)!
Then the mooose would bleed out and die a sad death on screen.
O and Reg could ride off on that tandem bike with their matching hats/bonnets.
Very moving, very compelling.
They would only affect other viruses that have the same overall characteristics. I think that HIV and Ebola are different enough that the same antivirals would not work on both viruses.
Probably the person who would have found the cure for ebola was aborted by his/her mother.
Maybe because I'm really tired, but I don't see the Tekmira drug mentioned in the article you linked.
The last I read about the Tekmira drug was that the phase 1 clinical trials had been halted and have not, to my knowledge, been restarted.
The HIV drugs may or may not help, they are fairly specific. The reason the platelets drop and the patients bleed is actually because they clot everywhere. The virus causes clotting in all the smallish vessels, using up all the clotting factors and platelets, so the patients have nothing left to clot with and bleed everywhere
The medical name is DIC, or disseminated intravascular coagulation. Giving platelets rarely helps as they are just used up as fast as the patients own platelets. The immune system works just fine in these folks, unlike in HIV
The only treatment I am aware of is supportive care - fluids, pain relief etc, and the mortality rate is very high. Lots of work to be done on a very nasty disease we have now voluntarily invited on our soil. Lets hope the CDC has learned from some recent horrific breaches, and things go well, but I’m not very optomistic.
“CAMPAIGNERS URGE U.S. AUTHORITIES TO GIVE EBOLA DRUG GREEN LIGHT
Health campaigners are calling for U.S. authorities to speed up their approval of a new drug hoped to be the first cure for the deadly Ebola virus.
A petition, created on change.org, states: ‘One of the most promising is TKM-Ebola manufactured by Tekmira Pharmaceuticals.
‘This drug has been shown to be highly effective in killing the virus in primates and Phase 1 clinical trials to assess its safety in humans were started earlier this year.’”
But it was in phase III trials for influenza if it’s the compound I’m thinking of.
Rabies is scary and used to be 100% fatal regardless. Pasteur provided a good chance with his vaccine, which works well if you know you need it in time. And if you’re at high enough risk I presume you can get the vaccine prophylactically. And now the Milwaukee protocol provides a smidgen of hope if you don’t seek Pasteur in time: a half dozen survivors out of three dozen attempts. Not great odds, but no longer 100% fatal once symptoms appear. I know you can get rabies without realizing you’ve been exposed, but absent vampire batswhich we do lack hereI think most victims would have at least some clue to get the shots. And the shots aren’t nearly as bad they used to be.
I see the best Gasto in Memphis, he treats my Drug induced GERD, and clearly states long term use of Nexium or other acid blockers, causes Barret’s Esophagus.
Nexium
Bone density side effects, and Barret’s Esophagus
http://www.valleyhealthcancercenter.com/Cancer-Services/Barretts-Esophagus - GERD treatment
I have to have a Upper GI biopsy every 2 yrs for it.
True, which is why I call it an incestuous relationship.
The Tekmira drug and the drug in phase 3 trials for influenza are different drugs, made by different companies. They work in different ways.
Ok.
I’ve got so many pubmed windows open on so many different articles right now. I need to clean them up and sort them.
I am well aware of the specifics of rabies infection. What scares me is that bats have tiny bites, and sometimes people do not know they have been bitten. There was a recent case where the incubation period was years (determined because the patient was living in Australia for several years before developing rabies). Rabies is endemic in my area--several rabid animals have been found this year.
All of the successful Milwaukee Protocol attempts that I am aware of were young girls. I do not know if that is significant. I will continue to consider rabies 100% fatal once symptoms appear until a better protocol has been worked out.
I know a woman who was bitten by a rabid bat. I think she had been previously vaccinated. In any case, she is still alive, several months later.
Indeed. I am reading dozens of articles. The only way to keep everything straight is to print and catalog it.
we hope. let’s take a poll, what country will be first
with one?
Thank God for the real men who founded this country,
and for the real men who continue to sustain it
Please join the 300 by donating $100
Food for thought about the question posted.
The key to finding a vaccine for a virus is to manipulate the immune system to be primed to react to its presence. That is typically done with either a "dead" virus or an attenuated one, that is, one that displays the glycoprotein markers without causing the disease. This particular virus has a fantastically low threshold dose, perhaps as few as 10 virii. A vaccine would have to be perfect not to kill the patient, perfect to a level that process science could produce consistently. It might be done, yes, but not within the parameters that are perfectly safe for, say, mumps or chicken pox.
The challenge isn't doing it to make a profit, it's doing it at all.
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