Its not the dose its the 24 hour total that is the problem. A single dose of 650-1000 mg is fine. But one shouldn’t exceed 4000 mg daily in the short term and prob 3000 mg daily in the long term or liver damage may result.
My mom has been popping Excedrins like candy for decades now. Don’t know how her liver is, but she is fine, so it is probably too. Still, I personally am very careful with the stuff.
Exactly right...My MIL has arthritis and broke a hip over ten years ago, she takes 650 mg doses 5 times a day, her doctors over the years have said exactly what you’ve posted.
The only thing is that my wife is careful not to buy any other meds she may need temporarily that contain Acetaminophen and there are many many that do.