In the mid 80’s I inspected a string of 9 5/8” drill pipe that was to be used for offshore mining, it’s like a deep dredging operation from what I understand.
One of the problems they had with the mining was the hydrates would come up with what they were mining for and could blow up the mining ships if they didn’t get rid of it fast enough.
The ship also had to be far enough away from where they were mining because they hydrates would release all at once and there would be a huge bubble of gas released.
It is methane. The oil/gas industry is quite used to handling methane.
If you want to mix it with air and keep it near ignition sources, it will react the same as any other natural gas source.
The hydrates do not exist directly on the top layer of the sea bed. They are buried, typically hundreds of feet deep.