It is methane. The oil/gas industry is quite used to handling methane.
If you want to mix it with air and keep it near ignition sources, it will react the same as any other natural gas source.
The hydrates do not exist directly on the top layer of the sea bed. They are buried, typically hundreds of feet deep.
The oil and gas industry is used to handling the controlled release of oil and gas.
Uncontrolled release is called a blowout.
It happens.
The mining ships found hydrates on the surface or right below the surface, when it’s disturbed it can release all at once like a well blowing out only on a much larger scale, several acres in size so they said.